Stable liquid formulations of recombinant fusion proteins

A liquid formulation of a recombinant fusion protein,

• which comprises a recombinant fusion protein, a buffer salt, a stabilizer, a surfactant and sterile water for injection, wherein,
• the recombinant fusion protein has a concentration of 5 to 45 mg/mL;
• the buffer salt is citrate salt, acetate salt or any combination thereof, and has a concentration of 5 to 25 mmol/L;
• the stabilizer is an amino acid or a combination of a polyol and an amino acid, wherein the amino acid is arginine, and the polyol is sucrose;
• the amino acid has a concentration of 50 to 350 mmol/L;
• and the polyol has a concentration of 1-15 wt %, based on total weight of the liquid formulation;
• the surfactant is polysorbate 20 and has a concentration of 0.01-0.08 wt %, based on total weight of the liquid formulation;
• and the pH of the liquid formulation is from 5.5 to 7.5;
• and
• the recombinant fusion protein is a recombinant fusion protein of human vascular endothelial growth factor receptor-antibody-human complement receptor 1 which comprises the amino acid sequence as set forth in SEQ ID NO:
• 1 or SEQ ID NO:
• 4.