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US 10,293,041 B2Granted
Multivalent stable vaccine composition and methods of making same
AssigneeSoligenix, Inc.
InventorsRobert Brey, Christopher Schaber
Life of this patent
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AssigneeSoligenix, Inc.
InventorsRobert Brey, Christopher Schaber
Estimating the term…
Stable immunogenic composition capable of eliciting a robust and durable immune response yielding a measurable increase in neutralizing antibodies at least 200 days post-administration, comprising at least one antigen consisting of a ribosome inactivating protein and at least one antigen comprising a toxin derived from bacterial spores. Method making and using a stable immunogenic composition capable of eliciting a stable immune response yielding a measurable increase in neutralizing antibodies at least 200 days post-administration, comprising providing an immunogenic composition comprising at least one antigen comprising a ribosome inactivating protein and at least one antigen comprising a toxin derived from bacterial spores and administering the immunogenic composition to an individual.
An immunogenic composition comprising a first antigen comprising a ribosome inactivating protein and a second antigen comprising a toxin derived from bacterial spores, wherein the immunogenic composition is formulated to elicit protective immunity to each of the first and second antigenic components without causing immune interference between the first and the second antigens after administration to an individual, further comprising at least one disaccharide glass forming excipient, aluminum hydroxide, an effective amount of glycopyranoside lipid A, and a buffer consisting of 50% glycerol buffer and 50% histidine buffer.
Dependencies are inferred from the claim text.