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US 10,293,026 B2Granted
Agent for preventing or treating demyelinating disease
AssigneeOsaka University
InventorsRieko Ikeda, Mariko Kuroda, Toshihide Yamashita
Life of this patent
Estimating the term…
Abstract
An object of the present invention is to provide a pharmaceutical preparation that can promote the proliferation of oligodendrocyte precursor cells to effectively prevent or treat a demyelinating disease. FGF21 acts to promote the proliferation of oligodendrocyte precursor cells, and thus, the administration of FGF21, DNA encoding FGF21, an FGF21 production-promoting substance, and/or FGF21-producing cells is effective for preventing or treating a demyelinating disease.
Claims4
A method for treating a demyelinating disease comprising:
- identifying an individual as having a demyelinating disease, and
- administering to the individual as an active ingredient FGF21 in an amount effective for the treatment.
A method for repairing myelin sheath comprising:
- identifying an individual as being in need of repair of myelin sheath, and
- administering, to the individual as an active ingredient FGF21 in an amount effective for repairing myelin sheath.
Dependencies are inferred from the claim text.