Methods of using extracts of melissa officinalis against filoviruses
AssigneeArizona Board of Regents on behalf of Arizona State University
InventorsJeffrey Langland, Bertram Jacobs, Karen Denzler
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Abstract
The present disclosure relates to methods of using Melissa officinalis extracts in inhibiting viral replication of a filovirus and in treating or preventing a filovirus infection.
Claims19
A method of inhibiting viral replication of a filovirus, the method comprising exposing the filovirus or a filovirus-infected cell to an effective amount of an extract from Melissa officinalis, or a composition comprising the extract, wherein the exposing inhibits viral replication within the cell.
A method of treating filovirus infection of a cell, the method comprising exposing a filovirus or filovirus-infected cell to an effective amount of an extract from Melissa officinalis, or a composition comprising the extract, wherein the exposing inhibits the entry of the filovirus into the cell.
A method of preventing filovirus infection of a cell, the method comprising exposing the cell to an effective amount of an extract from Melissa officinalis, or a composition comprising the extract, prior to exposure of the cell to the filovirus, wherein the exposing the cell to the Melissa officinalis extract, or a composition comprising Melissa officinalis extract inhibits filovirus infection.
A method of treating a subject infected with filovirus, the method comprising administering an effective amount of an extract from Melissa officinalis, or a composition comprising the extract, to the subject, thereby treating the subject infected with filovirus.
A method of preventing infection of a subject with filovirus, the method comprising administering an effective amount of an extract from Melissa officinalis, or a composition comprising the extract, to the subject prior to exposure of the subject to filovirus, thereby preventing infection with filovirus.
Dependencies are inferred from the claim text.