Applications for estrone in preparing anti-ovarian cancer and/or breast cancer products
AssigneeShanghai Jiao Tong University
InventorsYongyong Shi, Zhijian Song
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Abstract
This invention discloses uses for estrone in preparing anti-ovarian cancer and/or breast cancer products. This invention provides uses for estrone in the preparation of products to treat ovarian cancer and/or breast cancer. From carrying out cancer drug repositioning for the FDA- and CFDA-approved drug estrone, experiments for this invention show, based on screening of non-anti-cancer drugs for various cancer cell lines (tissue types) and mutation sites, that estrone has a new use as an anti-ovarian cancer and/or anti-breast cancer medication, thus achieving a new purpose for an old drug.
Claims4
A method for treating ER-negative breast cancer in a subject comprising administering an effective amount of estrone to a subject in need thereof.
A method of inhibiting the proliferation of ER-negative breast cancer cells comprising contacting the cells with an effective amount of estrone.
Dependencies are inferred from the claim text.