Method of treatment with anti-inflammatory and analgesic compounds which are GI-, renal-, and platelet-sparing
AssigneePathologica LLC
InventorsJohn McKearn, Jeremy Blitzer
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Abstract
Disclosed herein are compounds, pharmaceutical compositions, and methods for the treatment of diseases such as inflammation and/or pain, comprising the administration of a therapeutically effective amount of a non-steroidal, non-opioid compound having GI-/renal-/platelet-sparing activities, and wide safety margins with no appreciable inhibition of either form of cyclooxygenase.
Claims18
A method of treatment of pain or inflammation in an elderly patient in need thereof, comprising administering a therapeutically effective amount of methylglyoxal bis(guanylhydrazone) (MGBG), wherein the therapeutically effective amount of MGBG does not inhibit cyclooxygenase and is not an opioid or a steroid, and is gastrointestinal-, platelet-, and renal-sparing.
Dependencies are inferred from the claim text.