Biological heart valve replacement, particularly for pediatric patients, and manufacturing method

A biological heart valve replacement comprising:

• a tubular segment comprising a proximal end, a distal end, and a central portion arranged between said proximal and distal ends, defining a longitudinal direction of the valve and having an inner wall region, the valve further comprising
• at least one inner leaflet attached, in hinge-like manner, to a connection zone at the inner wall region of said central portion,
• each one of said inner leaflets being movable between a closing position and an opening position of the valve, wherein said tubular segment comprises at least one tubular growth zone in form of a longitudinal strip made of a growth-adaptive biomaterial adapted to increase its size concomitantly with surrounding organ structures of a host, with the remainder of the tubular segment being made of a non-growth-adaptive biomaterial, wherein said non-growth-adaptive biomaterial is a fixed xenogenic tissue or a homogenic native tissue.

A biological heart valve replacement comprising:

• a tubular segment comprising a proximal end, a distal end, and a central portion arranged between said proximal and distal ends, defining a longitudinal direction of the valve and having an inner wall region, the valve further comprising
• at least one inner leaflet attached, in hinge-like manner, to a connection zone at the inner wall region of said central portion,
• each one of said inner leaflets being movable between a closing position and an opening position of the valve, wherein said tubular segment comprises at least one tubular growth zone in form of a longitudinal strip made of a growth-adaptive biomaterial adapted to increase its size concomitantly with surrounding organ structures of a host, with the remainder of the tubular segment being made of a non-growth-adaptive biomaterial, wherein said growth-adaptive biomaterial is a tissue engineered material.