Modified cyanobacteria
AssigneesKao Corporation, Saitama University
InventorsAkihito Kawahara, Yukako Sonoike, Ayumi Kizawa
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Abstract
Provided is a cyanobacterium improved in fatty acid productivity. A method for producing a modified cyanobacterium, comprising causing loss of function of a LexA transcriptional regulator and acyl-ACP synthetase in a cyanobacterium.
Claims19
A method for producing a modified cyanobacterium, comprising deleting or inactivating the cyanobacterium's transcriptional regulator LexA and acyl-ACP synthetase genes, wherein the cyanobacterium is a member of the Synechocystis sp., Synechococcus sp. or Anabaena sp., and wherein the total amount of C12 to C18 free fatty acids that is produced by the modified cyanobacterium is greater than that produced by the unmodified cyanobacterium.
A method for improving fatty acid secretory productivity in a cyanobacterium, comprising deleting or inactivating the cyanobacterium's transcriptional regulator LexA and acyl-ACP synthetase genes, wherein the cyanobacterium is a member of the Synechocystis sp., Synechococcus sp. or Anabaena sp. and wherein the total amount of C12 to C18 free fatty acids that is produced by the modified cyanobacterium is greater than that produced by the unmodified cyanobacterium.
Dependencies are inferred from the claim text.