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US 10,287,280 B2Granted
Crystalline forms of (S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-4H-1,2,4-triazole-3-carboxamide
AssigneeGlaxoSmithKline Intellectual Property Development Limited
InventorsAnn Marie Diederich, Robert Herrmann
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Abstract
Disclosed are novel crystalline forms of (S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-4H-1,2,4-triazole-3-carboxamide, and solvates thereof and pharmaceutical compositions containing the same. Also disclosed are processes for the preparation thereof and methods for use thereof.
Claims19
A crystalline form of a compound represented by:
- wherein the crystalline form is a crystalline solvate of the compound and the crystalline solvate is selected from the group consisting of a methyl acetate, n-propyl acetate, isopropyl acetate, water, iso-propyl alcohol, methyl-isobutylketone, 2-methyl-tetrahydrofuran, dimethyl carbonate, and methoxy-cyclopentane solvate of the compound, wherein the water solvate is a monohydrate.
Dependencies are inferred from the claim text.