Back to results
US 10,274,453 B2Granted
Nanostructured microelectrodes and biosensing devices incorporating the same
AssigneeThe Governing Council of the University of Toronto
InventorsLeyla Soleymani, Zhichao Fang, Shana Kelley, Edward Sargent, Bradford Taft
Life of this patent
Estimating the term…
Abstract
Nanostructured microelectrodes and biosensing devices incorporating the same are disclosed herein.
Claims48
A biosensing workstation comprising:
- a cartridge holder for holding a biosensing cartridge, the biosensing cartridge including a sample chamber for containing a biological sample and a biosensing chamber containing a biosensing device, the biosensing device including:
- a substrate;
- an electrically conductive lead on the substrate;
- an insulating layer covering the lead, the insulating layer having an aperture exposing a portion of the lead;
- a nanostructured microelectrode, the microelectrode in electrical communication with the exposed portion of the lead, the microelectrode adapted to generate a charge in response to a biomolecular stimulus;
- and
- a charge storage in electrical communication with the lead for storing charge from the microelectrode, the charge on the charge storage at the end of an integration period indicative of the biomolecular stimulus;
- an instrument tip for accessing the biosensing cartridge;
- a selection mechanism for selecting a biosensing process to be carried out;
- a processor adapted to carry out the biosensing process using the biosensing cartridge and to determine results of the biosensing process from electronic signals generated from the biosensing cartridge;
- and
- a display for displaying the results of the biosensing process.
9 more elements
A biosensing workstation comprising:
- a cartridge holder for holding a biosensing cartridge, the biosensing cartridge including a sample chamber for containing a biological sample and a biosensing chamber containing a biosensing device, the biosensing device including:
- a substrate;
- an electrically conductive lead on the substrate;
- an insulating layer covering the lead, the insulating layer having an aperture exposing a portion of the lead;
- a nanostructured microelectrode, the microelectrode being in electrical communication with the exposed portion of the lead, the microelectrode being adapted to generate a charge in response to a biomolecular stimulus;
- and
- a charge storage in electrical communication with the lead for storing charge from the microelectrode, the charge on the charge storage at the end of an integration period indicative of the biomolecular stimulus;
- an instrument tip for accessing the biosensing cartridge;
- a processor adapted to carry out a biosensing process using the biosensing cartridge and to determine results of the biosensing process from electronic signals generated from the biosensing cartridge;
- and
- a display for displaying the results of the biosensing process.
8 more elements
Dependencies are inferred from the claim text.