Synergistic antibacterial effects of magnolia bark extract and L-arginine, N-α-lauroyl ethyl ester on plaque biofilm
AssigneeWm. Wrigley Jr. Company
InventorsMichael W. Dodds, Minmin Tian, Taichi Inui, Lilian Ramirez, Marcelo B. Aspiras
Life of this patent
Estimating the term…
Abstract
The present disclosure relates generally to oral compositions and methods for inhibiting the formation of plaque biofilm by salivary bacteria, and more particularly, to oral compositions comprising a combination of magnolia bark extract (MBE) and L-arginine, Nα-lauroyl ethyl ester (LAE). The oral compositions are useful for improving oral health, including inhibiting the formation of plaque biofilm by salivary bacteria and reducing plaque adherence to teeth.
Claims26
An oral composition for inhibiting the formation of plaque biofilm by salivary bacteria in an oral cavity of a consumer, the composition comprising magnolia bark extract (MBE) and L-arginine, Nα-lauroyl-ethyl ester (LAE), wherein the oral composition comprises the MBE and LAE in amounts that provide a synergistic inhibition of the formation of plaque biofilm in the oral cavity.
A coated oral composition for inhibiting the formation of plaque biofilm by salivary bacteria in an oral cavity of a consumer, the coated oral composition comprising MBE and LAE in a weight ratio from about 16:1 to about 4:1 that provide a synergistic inhibition of the formation of plaque biofilm in the oral cavity.
A method of making a coated oral composition, the method comprising:
- pretreating MBE and LAE to form a preblend mixture;
- adding the preblend mixture to a coating syrup;
- and,
- applying the coating syrup to an oral composition to produce the coated oral composition,
- wherein the coated oral composition comprises MBE and LAE in amounts that provide a synergistic inhibition of the formation of plaque biofilm by salivary bacteria in an oral cavity of a consumer.
Dependencies are inferred from the claim text.