Instrinsically antimicrobial porosic matrix composites and method of manufacture thereof
OwnerJohn Paul Wilsoninventor
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Abstract
A method of manufacturing a flexible intrinsically antimicrobial absorbent porosic composite controlling for an effective pore size using removable pore-forming substances and physically incorporated, non-leaching antimicrobials. A flexible intrinsically antimicrobial absorbent porosic composite controlled for an effective pore size composited physically incorporated, high-surface area, non-leaching antimicrobials, optionally in which the physically incorporated non-leaching antimicrobial exposes nanopillars on its surface to enhance antimicrobial activity. A kit that enhances the effectiveness of the intrinsically antimicrobial absorbent porosic composite by storing the composite within an antimicrobial container.
Claims12
A method of manufacturing an absorbent non-leaching antimicrobial porous matrix composite, comprising:
- making or obtaining a flexible porous solid matrix substrate that forms a pore-containing solid matrix, wherein the pores of the flexible porous solid matrix substrate have an average size of under 3 mm in width at their narrowest dimension;
- physically incorporating a non-leachable antimicrobial within or upon a pore-containing solid matrix, wherein the pore-containing matrix comprises a plurality of matrix pores, wherein each matrix pore comprises an interior, and wherein the non-leachable antimicrobial has exposure to the interior of the matrix pores;
- removing any non-physically incorporated non-leachable antimicrobial from the pore-containing solid matrix,
- wherein the non-leachable antimicrobial is physically incorporated within the pore-containing solid matrix by the step comprising:
- mixing the non-leachable antimicrobial with a solidifiable matrix in flowable form with a removable pore-forming substance,
- wherein the surface area to volume ratio of non-leachable antimicrobial is greater than 6000:1 m−1 prior to compositing,
- and wherein the non-leachable antimicrobial is evenly distributed and physically enveloped within the solidifiable matrix,
- and wherein the solidifiable matrix is solidified while physically enveloping the pore-forming substance and the non-leachable antimicrobial to form the pore-containing solid matrix, and wherein the non-leachable matrix antimicrobial represents <5% wt/wt of a dried form of the absorbent non-leaching antimicrobial porous structure composite.
A method of manufacturing an absorbent non-leaching antimicrobial porous matrix composite, comprising:
- making or obtaining a flexible porous solid matrix substrate that forms a pore-containing solid matrix, wherein the pores of the flexible porous solid matrix substrate have an average size of under 3 mm in width at their narrowest dimension;
- physically incorporating a non-leachable antimicrobial within or upon a pore-containing solid matrix, wherein the pore-containing matrix comprises a plurality of matrix pores, wherein each matrix pore comprises an interior, and wherein the non-leachable antimicrobial has exposure to the interior of the matrix pores;
- removing any non-physically incorporated non-leachable antimicrobial from the pore-containing solid matrix, wherein the non-leachable antimicrobial is physically incorporated within or upon the pore-containing solid matrix by the step comprising:
- physically chemically covalently attaching the non-leachable antimicrobial to the solid matrix,
- wherein the physically chemically covalently attached non-leachable antimicrobial is uniformly attached to the surface of the pores and irregularities of the solid matrix,
- and wherein the non-leachable antimicrobial represents <2.5% wt/wt of a dried form of the absorbent non-leaching antimicrobial porous structure composite;
- and further wherein at least 50 molecules of the non-leachable antimicrobial are anchored per cubic millimeter.
Dependencies are inferred from the claim text.