Methods for making L-glufosinate
AssigneeAgriMetis, LLC
InventorsBrian Michael Green, Michelle Lorraine Gradley
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Abstract
Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deamination of D-glufosinate to PPO (2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid). The second step involves the specific amination of PPO to L-glufosinate, using an amine group from one or more amine donors. By combining these two reactions, the proportion of L-glufosinate in a mixture of L-glufosinate and D-glufosinate can be substantially increased.
Claims22
A composition comprising D-glufosinate, 2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid (PPO), and L-glufosinate or a salt thereof, wherein L-glufosinate or the salt thereof is present in the composition at an amount of 80% by weight or greater based on the total amount of D-glufosinate, PPO, and L-glufosinate.
Dependencies are inferred from the claim text.