Back to results
US 10,259,884 B2Granted
Antibodies to GRP78
AssigneesWashington University, Vanderbilt University
InventorsDennis E. Hallahan, Heping Yan
Life of this patent
Estimating the term…
Abstract
The present invention is directed towards isolated antibodies that bind to GRP78.
Claims9
An isolated antibody that binds to 78-kDa glucose-regulated protein (GRP78), wherein the antibody comprises a heavy chain variable domain comprising a CDR1, CDR2, and a CDR3, wherein the heavy chain variable domain CDR1 comprises SEQ ID NO:
- 15, the heavy chain variable region domain CDR2 comprises SEQ ID NO:16, and the heavy chain variable region domain CDR3 comprises SEQ ID NO:17;
- and a light chain variable domain comprising a CDR1, CDR2, and CDR3, wherein the light chain variable domain CDR1 comprises SEQ ID NO:18, the light chain variable region domain CDR2 comprises SEQ ID NO:19, and the light chain variable region domain CDR3 comprises SEQ ID NO:20.
Dependencies are inferred from the claim text.