Display substrate and manufacturing method thereof, display device and manufacturing method thereof

A method for manufacturing a display substrate, the method comprising:

• providing a base including a first base portion and a second base portion adjacent the first base portion;
• forming a metal wire layer on the base, with a first metal wire layer portion of the metal wire layer formed directly on a first base portion of the base, or an organic buffer layer provided between a first metal wire layer portion of the metal wire layer and the first base portion of the base and the first metal wire layer portion positioned directly on the organic buffer layer;
• and
• at least one of:
• forming the inorganic insulating layer on the first base portion and the second base portion, and removing the inorganic insulating layer on the first base portion;
• or
• forming the inorganic insulating layer only on the second base portion so the inorganic insulating layer is positioned between the second base portion of the base and a second metal wire layer portion of the metal wire layer, the inorganic insulating layer including an inorganic buffer layer and a gate insulating layer, the metal wire layer including a gate metal layer, and sequentially forming an interlayer insulating layer, a passivation layer, a planarization layer, a pixel defining layer and a packaging layer on the gate metal layer;
• or
• forming the inorganic insulating layer only on the second base portion so the inorganic insulating layer is positioned between the second base portion of the base and a second metal wire layer portion of the metal wire layer, the inorganic insulating layer including the inorganic buffer layer, the gate insulating layer and an interlayer insulating layer, the metal wire layer including a source and/or drain metal layer, and sequentially forming the passivation layer, the planarization layer, the pixel defining layer and the packaging layer on the source and/or drain metal layer.