US 10,255,412 B2Granted

Real time adaptive controller medication dosing

AssigneeReciprocal Labs Corporation

InventorsChristopher Hogg, Gregory F. Tracy, John David Van Sickle, Dmitry Stupakov, Ki Hong Han, Mike Lohmeier, John Kalmi, Leah Morrell, Charles Clayton Donaldson

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Abstract

Systems and methods for monitoring accurate, real-time medicament device events, performing analytics on that data, and providing notifications are described. In various embodiments, an application server receives controller medication events, analyzes the events, associated event times, and controller medication dosage plans to characterize event times and send notifications for future doses. The controller medication dosage plan may specify a dose time for a planned dose, a narrow time window comprising the dose time, and an expanded time window comprising the narrow time window and longer in duration than the narrow time window, and the events may be characterized based on their time relative to the dose time, the time windows, and other events.

Claims30

Dependent claims

A method comprising:

receiving, at an application server, a first controller medication usage event at a first time from a computing device associated with a medicament device;
analyzing, at the application server, the first event, the first time, and a controller medication dosage plan, the controller medication dosage plan specifying a dose time for a planned dose, a narrow time window comprising the dose time, and an expanded time window comprising the narrow time window and longer in duration than the narrow time window, the analyzing comprising:
determining that the first time is not within the expanded time window;
responsive to determining that the first time is not within the expanded time window, characterizing the first event as an excessive dose;
responsive to determining that the first time is not within the expanded time window, generating a notification comprising a recommendation to a patient to not take the planned dose;
and
providing the notification to the computing device;
receiving, at the application server, a second controller medication usage event at a second time later than the first time from the computing device;
and
analyzing, at the application server, the first and second events, the first and second times, and the controller medication dosage plan to determine a dose characterization for the second event, the analyzing comprising:
determining that the second time is within the expanded time window;
and
characterizing the second event as one of an on time dose and an off schedule dose.

10 more elements

A method comprising:

receiving, at an application server, a first controller medication usage event at a first time from a computing device associated with a medicament device;
analyzing, at the application server, the first event, the first time, and a controller medication dosage plan to determine a dose characterization for the first event, the controller medication dosage plan specifying a dose time for a planned dose, a narrow time window comprising the dose time, and an expanded time window comprising the narrow time window and longer in duration than the narrow time window, the analyzing comprising:
determining that the first time is within the narrow time window;
and
responsive to determining that the first time is within the narrow time window, characterizing the first event as an on time dose;
receiving, at the application server, a second controller medication usage event at a second time later than the first time from the computing device;
and
analyzing, at the application server, the first and second events, the first and second times, and the controller medication dosage plan, the analyzing comprising:
determining that the second time is not closer to the dose time than the first time;
and
responsive to determining that the second time is not closer to the dose time than the first time, characterizing the second event as an excessive dose.

8 more elements

A method comprising:

receiving, at an application server, a first controller medication usage event at a first time from a computing device associated with a medicament device;
analyzing, at the application server, the first event, the first time, and a controller medication dosage plan, the controller medication dosage plan specifying a dose time for a planned dose, a narrow time window comprising the dose time, and an expanded time window comprising the narrow time window and longer in duration than the narrow time window, the analyzing comprising:
determining that the first time is not within the expanded time window;
and
responsive to determining that the first time is not within the expanded time window, characterizing the first event as an excessive dose;
receiving, at the application server, a second controller medication usage event at a second time later than the first time from the computing device;
and
analyzing, at the application server, the first and second events, the first and second times, and the controller medication dosage plan to determine a new dose characterization for the first event, the analyzing comprising:
determining that the second time is outside of the expanded time window and farther in time from the dose time than the first time;
and
responsive to determining that the second time is not within the expanded time window and farther in time from the dose time than the first time, re-characterizing the first event as an off schedule dose instead of as an excessive dose.

8 more elements

A non-transitory computer readable storage medium comprising computer program instructions that, when executed by a computer processor, cause the computer processor to:

receive, at an application server, a first controller medication usage event at a first time from a computing device associated with a medicament device;
analyze, at the application server, the first event, the first time, and a controller medication dosage plan, the controller medication dosage plan specifying a dose time for a planned dose, a narrow time window comprising the dose time, and an expanded time window comprising the narrow time window and longer in duration than the narrow time window, the analyze comprising:
determine that the first time is not within the expanded time window;
responsive to determining that the first time is not within the expanded time window, characterize the first event as an excessive dose;
responsive to determining that the first time is not within the expanded time window, generate a notification comprising a recommendation to a patient to not take the planned dose;
and
provide the notification to the computing device;
receive, at the application server, a second controller medication usage event at a second time later than the first time from the computing device;
and
analyze, at the application server, the first and second events, the first and second times, and the controller medication dosage plan to determine a dose characterization for the second event, the analyze comprising:
determine that the second time is within the expanded time window;
and characterizing the second event as one of an on time dose and an off schedule dose.

9 more elements

A non-transitory computer readable storage medium comprising computer program instructions that, when executed by a computer processor, cause the computer processor to:

receive, at an application server, a first controller medication usage event at a first time from a computing device associated with a medicament device;
analyze, at the application server, the first event, the first time, and a controller medication dosage plan to determine a dose characterization for the first event, the controller medication dosage plan specifying a dose time for a planned dose, a narrow time window comprising the dose time, and an expanded time window comprising the narrow time window and longer in duration than the narrow time window, the analyze comprising:
determine that the first time is within the narrow time window;
and
responsive to determining that the first time is within the narrow time window, characterize the first event as an on time dose;
receive, at the application server, a second controller medication usage event at a second time later than the first time from the computing device;
and
analyze, at the application server, the first and second events, the first and second times, and the controller medication dosage plan, the analyze comprising:
determine that the second time is not closer to the dose time than the first time;
and
responsive to determining that the second time is not closer to the dose time than the first time, characterize the second event as an excessive dose.

8 more elements

A non-transitory computer readable storage medium comprising computer program instructions that, when executed by a computer processor, cause the computer processor to:

receive, at an application server, a first controller medication usage event at a first time from a computing device associated with a medicament device;
analyze, at the application server, the first event, the first time, and a controller medication dosage plan, the controller medication dosage plan specifying a dose time for a planned dose, a narrow time window comprising the dose time, and an expanded time window comprising the narrow time window and longer in duration than the narrow time window, the analyze comprising:
determining that the first time is not within the expanded time window;
and
responsive to determining that the first time is not within the expanded time window, characterizing the first event as an excessive dose;
receive, at the application server, a second controller medication usage event at a second time later than the first time from the computing device;
and
analyze, at the application server, the first and second events, the first and second times, and the controller medication dosage plan to determine a new dose characterization for the first event, the analyze comprising:
determining that the second time is outside of the expanded time window and farther in time from the dose time than the first time;
and
responsive to determining that the second time is not within the expanded time window and farther in time from the dose time than the first time, re-characterize the first event as an off schedule dose instead of as an excessive dose.

8 more elements

A system comprising:

a computer processor;
and
a non-transitory computer readable storage medium comprising computer program instructions that, when executed by the computer processor, cause the computer processor to:
receive, at an application server, a first controller medication usage event at a first time from a computing device associated with a medicament device;
analyze, at the application server, the first event, the first time, and a controller medication dosage plan, the controller medication dosage plan specifying a dose time for a planned dose, a narrow time window comprising the dose time, and an expanded time window comprising the narrow time window and longer in duration than the narrow time window, the analyze comprising:
determine that the first time is not within the expanded time window;
and
responsive to determining that the first time is not within the expanded time window, characterize the first event as an excessive dose;
responsive to determining that the first time is not within the expanded time window, generate a notification comprising a recommendation to a patient to not take the planned dose;
and
provide the notification to the computing device;
receive, at the application server, a second controller medication usage event at a second time later than the first time from the computing device;
and
analyze, at the application server, the first and second events, the first and second times, and the controller medication dosage plan to determine a dose characterization for the second event, the analyze comprising:
determine that the second time is within the expanded time window;
and characterizing the second event as one of an on time dose and an off schedule dose.

13 more elements

A system comprising:

a computer processor;
and
a non-transitory computer readable storage medium comprising computer program instructions that, when executed by the computer processor, cause the computer processor to:
receive, at an application server, a first controller medication usage event at a first time from a computing device associated with a medicament device;
analyze, at the application server, the first event, the first time, and a controller medication dosage plan to determine a dose characterization for the first event, the controller medication dosage plan specifying a dose time for a planned dose, a narrow time window comprising the dose time, and an expanded time window comprising the narrow time window and longer in duration than the narrow time window, the analyze comprising:
determine that the first time is within the narrow time window;
and
responsive to determining that the first time is within the narrow time window, characterize the first event as an on time dose;
receive, at the application server, a second controller medication usage event at a second time later than the first time from the computing device;
and
analyze, at the application server, the first and second events, the first and second times, and the controller medication dosage plan, the analyzing comprising:
determine that the second time is not closer to the dose time than the first time;
and
responsive to determining that the second time is not closer to the dose time than the first time, characterize the second event as an excessive dose.

11 more elements

A system comprising:

a computer processor;
and
a non-transitory computer readable storage medium comprising computer program instructions that, when executed by the computer processor, cause the computer processor to:
receive, at an application server, a first controller medication usage event at a first time from a computing device associated with a medicament device;
analyze, at the application server, the first event, the first time, and a controller medication dosage plan, the controller medication dosage plan specifying a dose time for a planned dose, a narrow time window comprising the dose time, and an expanded time window comprising the narrow time window and longer in duration than the narrow time window, the analyze comprising:
determine that the first time is not within the expanded time window;
and
responsive to determining that the first time is not within the expanded time window, characterize the first event as an excessive dose;
receive, at the application server, a second controller medication usage event at a second time later than the first time from the computing device;
and
analyze, at the application server, the first and second events, the first and second times, and the controller medication dosage plan to determine a new dose characterization for the first event, the analyze comprising:
determine that the second time is outside of the expanded time window and farther in time from the dose time than the first time;
and
responsive to determining that the second time is not within the expanded time window and farther in time from the dose time than the first time, re-characterize the first event as an off schedule dose instead of as an excessive dose.

11 more elements

Dependencies are inferred from the claim text.

Facts

Application: 15/351,197Filed 14 Nov 2016 · us provisional application
Priority: 13 Nov 2015
Published: US 2017/0140125 A118 May 2017
Granted: 9 Apr 2019
Term ends: Not estimatedThe source records don’t support an estimate.

Classification20 codes

G16H 20/13
Relating to drugs or medications, e.g. for ensuring correct administration to patients: delivered from dispensers
A61M 15/0001
Inhalators: details of inhalators; Constructional features thereof
A61M 15/009
Inhalators: using medicine packages with incorporated spraying means, e.g. aerosol cans
G08B 21/24
Status alarms: reminder alarms, e.g. anti-loss alarms