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US 10,254,567 B2Granted
UV-absorbing vinylic monomers and uses thereof
AssigneeNovartis AG
InventorsFrank Chang, Ryan DeSousa, Troy Vernon Holland, John Dallas Pruitt, Jared Nelson
Life of this patent
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Abstract
Described herein are water-soluble UV-absorbing vinylic monomers and their uses in preparing UV-absorbing contact lenses capable of blocking ultra-violet (“UV”) radiation and optionally (but preferably) violet radiation with wavelengths from 380 nm to 440 nm, thereby protecting eyes to some extent from damages caused by UV radiation and potentially from violet radiation. This invention also provides a UV-absorbing contact lens.
Claims5
A UV-absorbing vinylic monomer of any one of formula (I) to (VII)
- in which:
- R2 and R2′ independent of one other are H, CH3, CCl3, CF3, Cl, Br, OH, OCH3, or NR′R″ in which R′ and R″ independent of each other are H or C1-C4 alkyl;
- R1′ independent of each other are H, CH3, CCl3, CF3, Cl, Br, OH, OCH3, SO3H, SO3Na, or NR′R″ in which R′ and R″ independent of each other are H or C1-C4 alkyl;
- R9 is SO3Na,
- R9′ is H, SO3Na,
- R10 is methyl or ethyl;
- L1 is a direct bond or a linkage of
- L2 is a linkage of
- X1 is O or NRº;
- and
- Y2, and Y3 independent of one another are a C2-C4 alkylene divalent radical;
- Q2, and Q3 independent of one another are a (meth)acryloylamido or (meth)acryloyloxy group;
- m1 is zero or 1, provided that if m1 is zero, then Q2 is a (meth)acryloylamido group.
10 more elements
Dependencies are inferred from the claim text.