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US 10,252,239 B2Granted
Multi-phase oscillatory flow reactor
AssigneeMassachusetts Institute of Technology
InventorsMilad Abolhasani, Connor Wilson Coley, Klavs F. Jensen
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Abstract
According to some aspects, described herein is an automated droplet-based reactor that utilizes oscillatory motion of a droplet in a tubular reactor under inert atmosphere. In some cases, such a reactor may address current shortcomings of continuous multi-phase flow platforms.
Claims20
An oscillatory flow reactor comprising:
- a sample port;
- a carrier phase port;
- and
- a tubing having a centerline running through a lumen of the tubing from a first end of the tubing to a second end of the tubing, the tubing being curved such that an imaginary straight line intersects with the centerline at least twice such that at least two portions of the tubing are aligned and observable with a single optical port.
1 more element
A method of using an oscillatory flow reactor comprising:
- injecting an aqueous droplet into a tubing, the tubing having an inner surface comprising a fluoropolymer;
- injecting an organic substance droplet into the tubing;
- and
- producing oscillatory flow of the aqueous droplet and the organic substance droplet through application of alternating pressure to the tubing, such that the aqueous droplet moves through the organic substance droplet with each oscillation,
- wherein the oscillatory flow reactor further comprises:
- a housing supporting the tubing;
- a carrier phase port in fluid communication with the tubing;
- and
- a sample port in fluid communication with the tubing.
6 more elements
An oscillatory flow reactor comprising:
- a tubing having an inner surface comprising a fluoropolymer, such that an aqueous droplet moves through an organic substance droplet in the tubing during application of alternating pressure to the tubing;
- a housing supporting the tubing;
- a carrier phase port in fluid communication with the tubing;
- and
- a sample port in fluid communication with the tubing.
2 more elements
Dependencies are inferred from the claim text.