# US 10,246,459 B2 · Use of tetramic acid derivatives as nematicides > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,246,459 B2 - Document ID: US10246459B2 - Status: Granted - Kind: B2 - Application number: 15/729,686 - Filed: 2017-10-11 - Published: 2018-02-01 - Granted: 2019-04-02 - Earliest claimed: 2013-05-28 - Assignees: Syngenta Participations AG - Applicants: Syngenta Participations AG - Inventors: Fabienne Hatt; Anke Buchholz - Web page: https://patentgrep.com/patent/US10246459B2 ## CPC - C07D 471/10: Spiro-condensed systems - A01N 43/40: six-membered rings - A01N 43/90: having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system - A01N 47/06: containing —O—CO—O— groups; Thio analogues thereof - C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08) - A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS ## Abstract Use of a tetramic acid compound according to formula (I) or (I′) with a second nematicide as a treatment for crop plants to combat and control nematodes in the soil of said crop plants. ## Claims ### Claim 1 A method for reducing nematode damage to a plant comprising: i) applying a first composition with nematicidal properties to a seed prior to planting and/or to the soil surrounding a planted seed or plant; ii) and applying a second composition comprising a systemic nematicidal compound to an aerial plant part of said previously treated plant or plant produced from said previously treated seed; wherein the systemic nematicidal compound is selected from a compound according to the following formula: wherein G is hydrogen or a latentiating group; and A is hydrogen, C1-6alkyl, C1-6haloalkyl, or C1-6alkoxy; or an agrochemically acceptable salt or an N-oxide thereof. ### Claim 2 (depends on 1) The method according to claim 1, wherein a first composition with nematicidal properties is applied to a seed and to the soil surrounding a planted seed or plant, wherein the first composition applied to the seed is the same as or different from the first composition applied to the soil surrounding a planted seed or plant. ### Claim 3 (depends on 1) The method according to claim 1, wherein the first composition comprises a chemical nematicide. ### Claim 4 (depends on 3) The method of claim 3, wherein the chemical nematicide is selected from the group consisting of 1,2-dibromo-3-chloropropane, 1,2-dichloropropane, 1,2-dichloropropane with 1,3-dichloropropene, 1,3-dichloropropene, 3,4-dichlorotetrahydrothiophene 1,1-dioxide, 3-(4-chlorophenyl)-5-methylrhodanine, 5-methyl-6-thioxo-1,3,5-thiadiazinan-3-ylacetic acid, 6-isopentenylaminopurine, abamectin, acetoprole, alanycarb, aldicarb, aldoxycarb, benclothiaz, benomyl, butylpyridaben, cadusafos, carbofuran, carbon disulfide, carbosulfan, chloropicrin, chlorpyrifos, cloethocarb, cytokinins, dazomet, DBCP, DCIP, diamidafos, dichlofenthion, dicliphos, dimethoate, doramectin, emamectin, emamectin benzoate, eprinomectin, ethoprophos, ethylene dibromide, fenamiphos, fenpyrad, fensulfothion, fluensulfone, fosthiazate, fosthietan, furfural, GY-81, heterophos, imicyafos, imicyafos, iodomethane, isamidofos, isazofos, ivermectin, kinetin, mecarphon, metam, metam-potassium, metam-sodium, methyl bromide, methyl isothiocyanate, milbemycin oxime, moxidectin, Myrothecium verrucaria composition, oxamyl, oxamyl carbamate, phorate, phosphamidon, phosphocarb, sebufos, selamectin, spinosad, terbam, terbufos, tetrachlorothiophene, thiafenox, thionazin, triazophos, triazuron, xylenols, YI-5302 and zeatin. ### Claim 5 (depends on 4) The method of claim 4, wherein the chemical nematicide is selected from abamectin, fosthiazate or oxamyl carbamate. ### Claim 6 (depends on 4) The method of claim 4, wherein the chemical nematicide is selected from abamectin which is applied to the seed and/or to the soil surrounding the planted seed or plant. ### Claim 7 (depends on 1) The method according to claim 1, wherein the first composition comprises a biological nematicide. ### Claim 8 (depends on 7) The method of claim 7, wherein the biological nematicide is selected from the group consisting of Myrothecium verrucaria, Burholderia cepacia, Bacillus chitonosporus, Paecilomyces lilacinus, Bacillus amyloliquefaciens, Bacillus firmus, Bacillus subtillis, Bacillus pumulis, and Pasteuria spp., preferably Pasteuria nishizawae strain Pn1 and Pasteuria usgae. ### Claim 9 (depends on 1) The method according to claim 1, wherein the first composition, or the second composition, or both the first composition and the second composition, further comprises at least one insecticide or fungicide. ### Claim 10 (depends on 1) The method according to claim 1, wherein the latentiating group is selected from —C(═O)—Ra or —C(═O)—O—Rb; wherein Ra is selected from hydrogen, C1-C12alkyl, C2-C12alkenyl, C2-C12alkynyl, C1-C10haloalkyl and Rb is selected from C1-C12alkyl, C2-C12alkenyl, C2-C12alkynyl and C1-C10haloalkyl. ### Claim 11 (depends on 10) The method according to claim 10, wherein A is hydrogen. ### Claim 12 (depends on 11) The method according to claim 11, wherein G is or H. ### Claim 13 (depends on 10) The method according to claim 10, wherein A is methyl. ### Claim 14 (depends on 13) The method according to claim 13, wherein G is or H. ### Claim 15 (depends on 10) The method according to claim 10, wherein G is or H. ### Claim 16 (depends on 1) The method of claim 1, wherein A is hydrogen or methyl.