# US 10,245,394 B2 · Powder dispersion apparatus, method of making and using the apparatus, and components that can be used on the apparatus and other devices

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- Number: US 10,245,394 B2
- Document ID: US10245394B2
- Status: Granted
- Kind: B2
- Application number: 14/053,946
- Filed: 2013-10-15
- Published: 2014-02-06
- Granted: 2019-04-02
- Earliest claimed: 2006-10-25
- Applicants: Mark Glusker; George S Axford; William W Alston; John Palmer-Felgate; Jonathan Wilkins; Willard R Foss; Nagaraja Rao; Mark Postich; Neeraj Pakala; David S Maltz; Keith Ung
- Inventors: Mark Glusker; George S Axford; William W Alston; John Palmer-Felgate; Jonathan Wilkins; Willard R Foss; Nagaraja Rao; Mark Postich; Neeraj Pakala; David S Maltz; Keith Ung
- Web page: https://patentgrep.com/patent/US10245394B2

## CPC

- A61M 15/0028: {using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up}
- A61M 15/0005: {with means for agitating the medicament}
- A61M 15/0036: {hollow piercing means}
- A61M 15/0041: {with movable piercing or cutting means}
- A61M 15/0048: {the dosages being arranged in a plane, e.g. on diskettes}
- A61M 11/001: {Particle size control}
- A61M 15/0016: {located downstream of the dispenser, i.e. traversed by the product}
- A61M 15/0051: {the dosages being arranged on a tape, e.g. strips}
- A61M 15/0081: {Locking means}
- A61M 15/0093: {without arming or cocking, e.g. acting directly on the delivery valve}
- A61M 15/0096: {Hindering inhalation before activation of the dispenser}
- A61M 2016/0015: {inhalation detectors}
- A61M 2202/064: Powder
- A61M 2205/43: making noise when used correctly
- A61M 2205/581: by audible feedback
- A61M 2205/582: by tactile feedback
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

Methods and apparatuses for the pulmonary delivery of a composition, such as methods and apparatuses for dispersing dry powder medicaments for inhalation by a patient. Elements or aspects of the apparatuses, including receptacle puncturing, mechanisms, deoccluding devices, receptacle impacting devices, and receptacle lock devices or systems.

## Claims

### Claim 1

A powder dispensing apparatus, comprising:
a support for supporting a powder-containing blister, the blister having at least one wall;
an outlet for communicating a flow of powder to a user of the apparatus;
a feed tube communicating with the outlet, the feed tube structured and arranged to deliver powder from the blister to the outlet;
a deoccluding device arranged within the feed tube, the deoccluding device comprising a bent wire for puncturing the wall of the blister so as to allow an air flow from the blister and into the feed tube, and for deoccluding;
a blister impacting device comprising at least one arm that impacts the blister; and a cutting mechanism configured to create at least one air inlet opening in the wall of the blister, whereby air may be drawn into the blister to aerosolize the powder therein.

### Claim 2 (depends on 1)

The apparatus of claim 1, wherein the bent wire is a generally V-shaped wire, configured to puncture the wall of the blister so as to allow an air flow from the blister and into the feed tube.