# US 10,245,293 B1 · Pet food supplement > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,245,293 B1 - Document ID: US10245293B1 - Status: Granted - Kind: B1 - Application number: 14/836,640 - Filed: 2015-08-26 - Granted: 2019-04-02 - Earliest claimed: 2012-05-04 - Assignees: Vetnique Labs LLC - Applicants: Jamy A. Bascharon - Inventors: Jamy A. Bascharon - Web page: https://patentgrep.com/patent/US10245293B1 ## CPC - A61K 36/42: Cucurbitaceae (Cucumber family) - A61K 31/353: 3,4-Dihydrobenzopyrans, e.g. chroman, catechin - A61K 31/366: having six-membered rings, e.g. delta-lactones - A61K 31/702: Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages - A61K 31/7048: having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin {, digitoxin or digoxin} - A61K 31/732: Pectin - A61K 33/08: Oxides; Hydroxides - A61K 35/744: Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs - A61K 35/747: Lactobacilli, e.g. L. acidophilus or L. brevis - A61K 36/55: Linaceae (Flax family), e.g. Linum - A61K 36/899: Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane - A61K 38/4873: {Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H} - A61K 45/06: Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca - A23L 33/21: Addition of substantially indigestible substances, e.g. dietary fibres - A61K 2035/115: {Probiotics} - C12Y 304/22032: Stem bromelain (3.4.22.32) - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B) - C12Y: ENZYMES ## Abstract This disclosure relates to methods of treating anal gland disease in subjects. In particular, the disclosure provides supplement compositions useful for treatment of anal gland disease. Such compositions comprise a probiotic, a fiber source, and an anti-inflammatory agent. ## Claims ### Claim 1 A method of treatment or prevention of anal gland disease, the method comprising administering to a subject in need of such treatment an effective amount of one or more compositions comprising (1) a probiotic, a prebiotic, or both, (2) a fiber source, and (3) an anti-inflammatory agent selected from the group consisting of fish oil, bioflavonoid, bromelain, Vitamin C, Vitamin E, L-glutathione, selenium, resveratrol, papain, flax seed oil, curcumin, ginger, alpha lipoic acid, zinc, quercetin, and a combination thereof. ### Claim 2 (depends on 1) The method according to claim 1, wherein the subject is a dog or a cat. ### Claim 3 A method of treatment or prevention of anal gland disease, the method comprising administering to a subject in need of such treatment an effective amount of one or more compositions comprising (1) two or more fiber sources, (2) an anti-inflammatory agent selected from the group consisting of fish oil, bioflavonoid, bromelain, Vitamin C, Vitamin E, L-glutathione, selenium, resveratrol, papain, flax seed oil, curcumin, ginger, alpha lipoic acid, zinc, quercetin, and a combination thereof, and (3) optionally one additional agent selected from the group selected from a probiotic, a prebiotic, an anti-histamine, an antibiotic, and an anti-diarrhea agent. ### Claim 4 (depends on 3) The method according to claim 3, wherein the subject is a dog or a cat. ### Claim 5 A method of treatment or prevention of anal gland disease, the method comprising administering to a subject in need of such treatment an effective amount of one or more compositions comprising two or more fiber sources and an anti-inflammatory agent selected from bromelain, quercetin, or a combination thereof. ### Claim 6 (depends on 5) The method according to claim 5, wherein one fiber source is pumpkin or pumpkin seed. ### Claim 7 (depends on 1) The method according to claim 1, wherein the probiotic is a strain selected from the group consisting of Bifidobacterium, Lactobacillus, Lactococcus, Saccharomyces, Streptococcus, and a combination thereof. ### Claim 8 (depends on 7) The method according to claim 7, wherein the probiotic is Lactobacillus acidophilus. ### Claim 9 (depends on 1) The method according to claim 1, wherein the fiber source is selected from the group consisting of barley, flax seed, digestion resistant maltodextrin, beet pulp, guar gum, inulin, cellulose, larch arabinogalactan, methylcellulose, oat bran, oligofructose, pectin, pumpkin powder, pumpkin seed, psyllium, rice bran, wheat bran, wheat dextrin, and a combination thereof. ### Claim 10 (depends on 1) The method according to claim 1, wherein the anti-inflammatory agent is bromelain, quercetin, or a combination thereof. ### Claim 11 (depends on 1) The method according to claim 1, wherein the composition comprises: L. Acidophilus, pumpkin seed, quercetin, and bromelain. ### Claim 12 (depends on 3) The method according to claim 3, wherein the probiotic is a strain selected from the group consisting of Bifidobacterium, Lactobacillus, Lactococcus, Saccharomyces, Streptococcus, and a combination thereof. ### Claim 13 (depends on 12) The method according to claim 12, wherein the probiotic is Lactobacillus acidophilus. ### Claim 14 (depends on 3) The method according to claim 3, wherein the fiber source is selected from the group consisting of barley, flax seed, digestion resistant maltodextrin, beet pulp, guar gum, inulin, cellulose, larch arabinogalactan, methylcellulose, oat bran, oligofructose, pectin, pumpkin powder, pumpkin seed, psyllium, rice bran, wheat bran, wheat dextrin, and a combination thereof. ### Claim 15 (depends on 3) The method according to claim 3, wherein the anti-inflammatory agent is bromelain, quercetin, or a combination thereof. ### Claim 16 (depends on 3) The method according to claim 3, wherein the composition comprises: L. Acidophilus, pumpkin seed, quercetin, and bromelain. ### Claim 17 (depends on 1) The method according to claim 1, wherein the anti-inflammatory agent is quercetin, where quercetin is present in the amount of about 3 weight % to about 15 weight %. ### Claim 18 (depends on 17) The method according to claim 17, wherein the composition further comprising a digestive enzyme. ### Claim 19 (depends on 18) The method according to claim 18, wherein the digestive enzyme is bromelain. ### Claim 20 (depends on 18) The method according to claim 18, wherein the composition further comprising apple pectin. ### Claim 21 A method of treatment or prevention of anal gland disease, the method comprising administering to a subject in need of such treatment an effective amount of one or more compositions comprising (1) a probiotic, a prebiotic, or both, (2) a fiber source, and (3) an anti-inflammatory agent selected from the group consisting of fish oil, bioflavonoid, bromelain, Vitamin C, Vitamin E, L-glutathione, selenium, resveratrol, papain, flax seed oil, curcumin, ginger, alpha lipoic acid, zinc, quercetin, and a combination thereof, wherein the administration is oral. ### Claim 22 A method of treatment or prevention of anal gland disease, the method comprising administering to a subject in need of such treatment an effective amount of one or more compositions comprising (1) two or more fiber sources, (2) an anti-inflammatory agent selected from the group consisting of fish oil, bioflavonoid, bromelain, Vitamin C, Vitamin E, L-glutathione, selenium, resveratrol, papain, flax seed oil, curcumin, ginger, alpha lipoic acid, zinc, quercetin, and a combination thereof, and (3) optionally one additional agent selected from the group selected from a probiotic, a prebiotic, an anti-histamine, an antibiotic, and an anti-diarrhea agent, wherein the administration is oral. ### Claim 23 (depends on 21) The method according to claim 21, wherein the anti-inflammatory agent is bromelain, Vitamin C, Vitamin E, quercetin, or a combination thereof. ### Claim 24 (depends on 22) The method according to claim 22, wherein the anti-inflammatory agent is bromelain, Vitamin C, Vitamin E, quercetin, or a combination thereof.