# US 10,245,292 B2 · Composition for enhancing male sex hormone and men's health

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- Number: US 10,245,292 B2
- Document ID: US10245292B2
- Status: Granted
- Kind: B2
- Application number: 14/819,441
- Filed: 2015-08-06
- Published: 2015-11-26
- Granted: 2019-04-02
- Earliest claimed: 2013-02-08
- Assignees: Famenity Co., Ltd.
- Applicants: Famenity Co., Ltd.
- Inventors: Do Hee Kim; Yoon Hwa Jeong; Ji Won Lee; Yoo Hun Noh; Ji Ae Park; Seng Ah Lee
- Web page: https://patentgrep.com/patent/US10245292B2

## CPC

- A61K 36/288: Taraxacum (dandelion)
- A23L 33/00: Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L 33/10: using additives (addition of substantially indigestible substances A23L33/21)
- A23L 33/105: Plant extracts, their artificial duplicates or their derivatives
- A23L 33/30: {Dietetic or nutritional methods, e.g. for losing weight (A23L33/10 takes precedence)}
- A61K 36/48: Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61P 15/12: for climacteric disorders
- A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs
- A61K 2236/37: Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
- A61K 2236/51: Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION

## Abstract

The present disclosure relates to a use of a dandelion extract and a Rooibos extract. The present disclosure also relates to a food composition and a pharmaceutical composition for preventing and improving climacteric, including a dandelion extract, or a dandelion and Rooibos composite extract as an active ingredient.

## Claims

### Claim 1

A method of reducing the instance of, improving, or treating male climeractic disorder and symptoms thereof comprising:
administering an effective amount of a composition comprising a dandelion extract and a rooibos extract to a subject with male climeractic disorder, wherein the dandelion and rooibos extracts are obtained by extraction with a solvent selected from the group consisting of water, alcohol, and a mixture thereof; wherein the weight ratio of the dandelion extract and the rooibos extract is 4:1-1:9; and wherein the amount of the dandelion extract, or dandelion extract and rooibos extract, administered is from 0.01 mg/day/kg to 100 mg/day/kg of body weight.

### Claim 2 (depends on 1)

The method of claim 1, wherein the composition is a food composition.

### Claim 3 (depends on 1)

The method of claim 1, wherein the composition is a pharmaceutical composition.

### Claim 4 (depends on 1)

The method of claim 1, wherein the solvent is a C1-C6 alcohol.

### Claim 5 (depends on 1)

The method of claim 1, wherein the symptoms are at least one selected from the group consisting of testosterone deficiency syndrome, sex hormone precursor (DHEA) deficiency syndrome, a disease of increased level of sex hormone binding globulin, neurotic symptoms, anxiety disorder, anxiety, dizziness, facial flushing, sweating, sleep disturbance, hypotrophy, memory impairment, deterioration in work performance, hypoactive sexual desire disorder, erectile dysfunction, decrease of sperm motility, decrease of stamina, decrease of physical performance, decrease of exercise ability, decrease of body hair, skin aging, decrease of bone density, and increase of visceral fat.