# US 10,245,250 B2 · Method of improving visual processing, visual acuity, or both by administering compositions comprising RRR-alpha-tocopherol to infants

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- Number: US 10,245,250 B2
- Document ID: US10245250B2
- Status: Granted
- Kind: B2
- Application number: 15/977,390
- Filed: 2018-05-11
- Published: 2018-09-13
- Granted: 2019-04-02
- Earliest claimed: 2014-11-25
- Assignees: Abbott Laboratories
- Applicants: Abbott Laboratories
- Inventors: Matthew Kuchan; Chron-Si Lai; Jacqueline Boff
- Web page: https://patentgrep.com/patent/US10245250B2

## CPC

- A61K 31/355: Tocopherols, e.g. vitamin E
- A23L 33/12: Fatty acids or derivatives thereof
- A23L 33/15: Vitamins
- A23L 33/155: Vitamins A or D
- A23L 33/30: {Dietetic or nutritional methods, e.g. for losing weight (A23L33/10 takes precedence)}
- A23L 33/40: {Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula}
- A61K 31/01: Hydrocarbons
- A61K 31/015: carbocyclic
- A61K 31/047: having two or more hydroxy groups, e.g. sorbitol
- A61K 31/065: Diphenyl-substituted acyclic alcohols
- A61K 31/122: having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION

## Abstract

Methods for improving the visual processing of a healthy infant by administering a composition comprising RRR-alpha-tocopherol to the infant are disclosed. Methods for improving the visual acuity of a healthy infant by administering a composition comprising RRR-alpha-tocopherol to the infant are also disclosed. Methods for improving the development of the visual processing, visual acuity, or both, of an infant by administering a composition comprising RRR-alpha-tocopherol to the infant are also disclosed.

## Claims

### Claim 1

A method of improving the visual processing of a healthy infant, the method comprising administering a nutritional composition comprising RRR-alpha-tocopherol to the infant.

### Claim 2 (depends on 1)

The method of claim 1 wherein the nutritional composition delivers about 0.5 mg to about 100 mg of RRR-alpha-tocopherol per day to the infant.

### Claim 3 (depends on 1)

The method of claim 1 wherein the nutritional composition is a nutritional product further comprising at least one of protein, carbohydrate, and fat.

### Claim 4 (depends on 3)

The method of claim 3 wherein the nutritional product is an infant nutritional formula comprising about 2% to about 75% protein, about 1% to about 85% carbohydrate, and about 5% to about 70% fat as percentages of the total calories.

### Claim 5 (depends on 1)

The method of claim 1 wherein the nutritional composition is administered at least once per day.

### Claim 6 (depends on 1)

The method of claim 1 wherein the nutritional composition is a vitamin supplement.

### Claim 7

A method of improving the visual acuity of a healthy infant, the method comprising administering a nutritional composition comprising RRR-alpha-tocopherol to the infant.

### Claim 8 (depends on 7)

The method of claim 7 wherein the nutritional composition delivers about 0.5 mg to about 100 mg of RRR-alpha-tocopherol per day to the infant.

### Claim 9 (depends on 7)

The method of claim 7 wherein the nutritional composition is an infant nutritional formula further comprising at least one of protein, carbohydrate, and fat.

### Claim 10 (depends on 9)

The method of claim 9 wherein the nutritional product is an infant nutritional formula comprising about 2% to about 75% protein, about 1% to about 85% carbohydrate, and about 5% to about 70% fat as percentages of the total calories.

### Claim 11 (depends on 7)

The method of claim 7 wherein the nutritional composition is administered at least once per day.

### Claim 12 (depends on 7)

The method of claim 7 wherein the nutritional composition is a vitamin supplement.

### Claim 13

A method of improving the development of visual processing, visual acuity, or both visual processing and visual acuity in an infant, the method comprising administering a nutritional composition comprising RRR-alpha-tocopherol to the infant.

### Claim 14 (depends on 13)

The method of claim 13, wherein the nutritional composition delivers about 0.5 mg to about 100 mg of RRR-alpha-tocopherol per day to the infant.

### Claim 15 (depends on 13)

The method of claim 13 wherein the nutritional composition is an infant nutritional formula further comprising at least one of protein, carbohydrate, and fat.

### Claim 16 (depends on 13)

The method of claim 13 wherein the nutritional composition is administered at least once per day.

### Claim 17 (depends on 13)

The method of claim 13 wherein the nutritional composition is a vitamin supplement.

### Claim 18 (depends on 13)

The method of claim 13, wherein the infant is a premature infant or a full-term infant.

### Claim 19 (depends on 13)

The method of claim 13, wherein the infant does not have ocular disease.