# US 10,245,247 B2 · Omega-3 fatty acid articles of manufacture, and methods and apparatus for making same

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- Number: US 10,245,247 B2
- Document ID: US10245247B2
- Status: Granted
- Kind: B2
- Application number: 15/821,132
- Filed: 2017-11-22
- Published: 2018-08-09
- Granted: 2019-04-02
- Earliest claimed: 2013-12-06
- Assignees: Ambo Innovations, LLC
- Applicants: Ambo Innovations, LLC
- Inventors: Bo Martinsen; Leif Andreas Riege
- Web page: https://patentgrep.com/patent/US10245247B2

## CPC

- A61K 31/202: having three or more double bonds, e.g. linolenic (eicosanoids, e.g. leukotrienes A61K31/557)
- A23D 9/02: characterised by the production or working-up
- A23L 33/12: Fatty acids or derivatives thereof
- A61K 31/352: condensed with carbocyclic rings, e.g. methantheline {(cannabinoids A61K31/658)}
- A61K 31/353: 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K 31/355: Tocopherols, e.g. vitamin E
- A61K 31/4045: Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
- A61K 31/593: 9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
- A61K 35/60: Fish, e.g. seahorses; Fish eggs
- A61K 36/185: Magnoliopsida (dicotyledons)
- A61K 36/5777: {Theobroma, e.g. cocao or cocoa}
- A61K 36/82: Theaceae (Tea family), e.g. camellia
- C11B 1/10: by extracting
- C11B 5/0085: {Substances of natural origin of unknown constitution, f.i. plant extracts}
- C11B 5/0092: {Mixtures}
- A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs
- A61K 9/0053: {Mouth and digestive tract, i.e. intraoral and peroral administration}
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23D: EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS (preservation thereof A23B20/00; production, refinement or preservation of animal or vegetable fats or oils C11B, C11C)
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- C11B: PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES (drying-oils C09F)
- A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION

## Abstract

Embodiments of the present invention are directed to methods, apparatus and articles of manufacture that feature omega-3 fatty acids co-processed with flavonoid and lipophilic antioxidants for improved stability.

## Claims

### Claim 1

An article of manufacture comprising a lipid resulting from a source of omega-3 fatty acids co-processed with a hydrophilic flavonoid, a lipophilic anti-oxidant, and melatonin in a concentration effective to inhibit lipid destroying enzymes.

### Claim 2 (depends on 1)

The article of manufacture of claim 1 wherein said flavonoid is derived from one or more of the sources selected from tea, moringa and cacao.

### Claim 3 (depends on 1)

The article of manufacture of claim 1 wherein said hydrophilic flavonoid is present in 250-10,000 ppm.

### Claim 4 (depends on 1)

The article of manufacture of claim 1 wherein said lipophilic anti-oxidant is present in a concentration of 250-10,000 ppm.

### Claim 5 (depends on 1)

The article of manufacture of claim 1 wherein said lipophilic anti-oxidant is selected from the group consisting of carotenoids, alpha-tocopherol, retinol (vitamin A) and its derivatives and cholecalciferol (vitamin D3) and its derivatives.

### Claim 6 (depends on 1)

The article of manufacture of claim 1 incorporated in a food product.

### Claim 7 (depends on 1)

The article of manufacture of claim 1 further incorporated in a dosage form for administration of as a dietary, health supplement or as a medicament.

### Claim 8 (depends on 1)

The article of manufacture of claim 1 wherein said flavonoid is selected from the group consisting of (-) epicatechin, (-) epicatechin gallate, quercetin and EGCG.

### Claim 9 (depends on 1)

The article of manufacture of claim 1 wherein said omega-3 fatty acid is from a naturally occurring source.

### Claim 10 (depends on 9)

The article of manufacture of claim 9 wherein said naturally occurring source is selected from the group consisting of fish and marine animal, plant and algal sources.

### Claim 11 (depends on 1)

The article of manufacture of claim 1 wherein the source of omega-3 fatty acids is co-processed with the hydrophilic flavonoid, lipophilic anti-oxidant, and melatonin by a process selected from the group consisting of mincing, cutting, and grinding.