# US 10,245,219 B2 · Method for the removal of tattoos and skin discolouration > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,245,219 B2 - Document ID: US10245219B2 - Status: Granted - Kind: B2 - Application number: 14/581,657 - Filed: 2014-12-23 - Published: 2016-06-23 - Granted: 2019-04-02 - Earliest claimed: 2014-12-23 - Applicants: Klaus Böde - Inventors: Klaus Böde - Web page: https://patentgrep.com/patent/US10245219B2 ## CPC - A61K 8/365: Hydroxycarboxylic acids; Ketocarboxylic acids - A61B 17/32: Surgical cutting instruments ({A61B18/042 takes precedence; suture cutters A61B17/0467;} implements for ligaturing and cutting {A61B17/122, A61B17/12; instruments for rupturing the amniotic membrane A61B17/4208; specially adapted knives for eye surgery A61F9/0133}) - A61B 17/3209: Incision instruments - A61B 17/322: Skin grafting apparatus - A61K 8/14: Liposomes; Vesicles - A61Q 1/145: {Tattoo removal} - A61B 2017/00769: {Tattoo removal} - A61K 2800/91: Injection - A61M 37/0076: {Tattooing apparatus (apparatus for marking animals A01K11/00; vaccine applicators having needles or other puncturing means A61B17/205)} - A61M 37/0084: {Tattooing apparatus with incorporated liquid feeding device} - A61M 2210/04: Skin - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A method for the removal of tattoos or skin discoloration includes applying a removal fluid to the skin using a pigmentation device or a knife, such that the removal fluid is applied by small-scale, partial removal of the epidermis. In addition, the disclosure involves a removal fluid for use in the method. ## Claims ### Claim 1 A method for removal of tattoos or skin discoloration, the method comprising: applying from about 0.02 ml to about 0.5 ml of a removal fluid to a pigmentation device to form a wetted pigmentation device, the wetted pigmentation device comprising one or more needles; and with the wetted pigmentation device, forming a treatment area by contacting the one or more needles to an epidermis while traversing a path defining a circumference a maximum of 3 to 4 times in about 10-15 seconds to remove at least a portion of the epidermis bounded by the circumference, wherein the removal fluid from the wetted pigmentation device enters the treatment area during the forming the treatment area. ### Claim 2 (depends on 1) The method according to claim 1, wherein the removal fluid is encapsulated in liposomes and the removal fluid is transported by the liposomes, at the treatment area, into an upper dermis. ### Claim 3 (depends on 1) The method according to claim 1, further comprising setting a penetration depth of the one or more needles through a manual adjustment. ### Claim 4 (depends on 3) The method of claim 3, wherein the penetration depth is about 0.3 mm to about 0.5 mm. ### Claim 5 (depends on 1) The method of claim 1, wherein the removal fluid is introduced at an upper dermis and reaches a subcutis by way of a release of liposomes. ### Claim 6 (depends on 1) The method of claim 1, wherein the removal fluid exists in an encapsulated form. ### Claim 7 (depends on 6) The method of claim 6, wherein the removal fluid exists in one or more liposomal capsules. ### Claim 8 (depends on 7) The removal fluid of claim 7, wherein membranes of liposomes comprising the one or more liposomal capsules are less than 500 nanometers in diameter and shells of the one or more liposomal capsules are made of one or more shells. ### Claim 9 (depends on 1) The method of claim 1, wherein the removal fluid includes from about 10% wt. to about 80% wt. bleach acid. ### Claim 10 (depends on 9) The method of claim 9, wherein the bleach acid comprises at least one of hydrochloride, sodium hypochlorite, boric acid, sodium sulphite (Na2SO3) or sodium dithionite (Na2S2O4), hydrogen peroxide, β-hydroxy carboxylic acid, salicylic acid, or AHA-acids (α-hydroxy carboxylic acid), or a mixture thereof. ### Claim 11 (depends on 9) The method of claim 9, wherein the removal fluid includes from about 20% wt. to about 50% wt. bleach acid. ### Claim 12 (depends on 1) The method of claim 1, wherein the treatment area comprises a round or oval shape having an area that is from about 0.5 cm to about 0.8 cm across. ### Claim 13 A method of removing pigmentation from skin, the skin comprising an epidermis, a stratum basale beneath the epidermis, and a dermis beneath the stratum basale, the method comprising: applying a removal fluid to one or more needles; causing the one or more needles to move along a path defining a circumference; and contacting the one or more needles to the epidermis to remove at least a portion of the epidermis bounded by the circumference to form a treatment area, the one or more needles penetrating the epidermis at a depth less than a thickness of the epidermis to avoid penetrating the stratum basale and the dermis, wherein the removal fluid applied to the one or more needles is transferred from the one or more needles into the treatment area and mixes with wound fluid present in the treatment area, and wherein the contacting the one or more needles to the epidermis comprises contacting the one or more needles and traversing the path a maximum of 3 to 4 times in about 10-15 seconds. ### Claim 14 (depends on 13) The method of claim 13, wherein the treatment area comprises a first treatment area, the method further comprising forming a second treatment area spaced from the first treatment area. ### Claim 15 (depends on 14) The method of claim 14, wherein the second treatment area is spaced from the first treatment area by about at least 8 mm. ### Claim 16 (depends on 13) The method of claim 13, wherein the one or more needles move in a direction substantially parallel to a central axis of the path. ### Claim 17 (depends on 16) The method of claim 16, wherein the one or more needles move in the direction substantially parallel to the central axis at a frequency of about 150 stitches per second. ### Claim 18 (depends on 16) The method of claim 16, wherein the removal fluid includes from about 10% wt. to about 80% wt. bleach acid, and the bleach acid comprises at least one of hydrochloride, sodium hypochlorite, boric acid, sodium sulphite (Na2SO3) or sodium dithionite (Na2S2O4), hydrogen peroxide, β-hydroxy carboxylic acid, salicylic acid, or AHA-acids (α-hydroxy carboxylic acid), or a mixture thereof.