# US 10,245,108 B2 · Apparatus and method for producing very small microchannels in tissue

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- Number: US 10,245,108 B2
- Document ID: US10245108B2
- Status: Granted
- Kind: B2
- Application number: 15/679,118
- Filed: 2017-08-16
- Published: 2018-04-26
- Granted: 2019-04-02
- Earliest claimed: 2014-06-10
- Assignees: Lumenis Ltd.
- Applicants: Lumenis Ltd.
- Inventors: Zipora Ozer Armon; Eyal Benisty; Arie Kraisler; Roy Ramati
- Web page: https://patentgrep.com/patent/US10245108B2

## CPC

- A61B 18/203: {applying laser energy to the outside of the body}
- G02B 9/34: having four components only
- G02B 13/04: Reversed telephoto objectives
- G02B 26/105: {with one or more pivoting mirrors or galvano-mirrors (G02B26/101 takes precedence)}
- A61B 18/14: Probes or electrodes therefor
- A61B 2018/00005: {Cooling or heating of the probe or tissue immediately surrounding the probe}
- A61B 2018/00452: {Skin}
- A61B 2018/00458: {Deeper parts of the skin, e.g. treatment of vascular disorders or port wine stains}
- A61B 2018/0047: {Upper parts of the skin, e.g. skin peeling or treatment of wrinkles}
- A61B 2018/20351: {Scanning mechanisms}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G02B: OPTICAL ELEMENTS, SYSTEMS OR APPARATUS

## Abstract

A lens system includes: a plurality of aligned lenses; a first lens having negative refractive power; a second lens having negative refractive power; a third lens with positive refractive power; and, a fourth lens with positive refractive power; a light beam transmitted through the first, second, third and fourth lenses is first diverged by the first and second lenses, collimated by the third lens and focused by the fourth lens to form a small spot at the focal plane.

## Claims

### Claim 1

A method of producing small microchannels on a skin tissue surface while maintaining a 50 mm standoff distance from the skin tissue surface comprising:
providing a lens system having:
a plurality of aligned lenses;
one or more scanning mirrors in line with and upstream of the plurality of aligned lenses and a source of laser energy upstream of the one or more scanning mirrors, wherein laser light beam from the laser source is transmitted from the source of laser energy, deflected by the one or more scanning mirrors and then transmitted through the aligned lenses;
a first diverging beam lens of the plurality of aligned lenses downstream of the one or more scanning mirrors having negative refractive power;
a second converging beam lens of the plurality of aligned lenses downstream of the first lens having positive refractive power;
a third converging beam lens of the plurality of aligned lenses downstream of the second lens having positive refractive power; and,
a fourth converging beam lens of the plurality of aligned lenses downstream of the third lens with positive refractive power;
wherein the laser light beam exiting from the laser source is 7 mm in diameter, diverges to 12 mm after being transmitted through the first and the second lenses, enters the third lens with a 12 mm diameter, and converges to 70 microns on the focal plane after being transmitted through the third and fourth lenses;
the method comprising:
transmitting a laser light beam of 7 mm in diameter from the source of laser energy to impinge on the first lens;
transmitting the laser light beam through the first and second lenses, whereby the light beam diverges to 12 mm;
transmitting the diverged light beam to the third lens, the third lens collimating the light beam; and,
transmitting the light beam from the third lens to the fourth lens, the fourth lens converging the light beam to produce 70 micron microchannel spots at a standoff distance of 50 mm from the vertex of the fourth lens at the skin tissue surface.

### Claim 2 (depends on 1)

The method of claim 1, further comprising one or more motors to control the one or more scanning mirrors, a programmed controller in operative connection to the one or more motors, wherein the controller is programmed to move the one or more scanning mirrors in a selected pattern.

### Claim 3 (depends on 1)

The method of claim 1, wherein the first lens is of meniscus shape with radii of curvature of 20.61 mm and 50.15 mm, the second lens is of meniscus shape with radii of curvature of 35.1 mm and 28.35 mm, the third and fourth lenses are identical and of meniscus shape with radii of curvature of 163.35 mm and 61.19 mm.