Resolution enhancement of diffusion imaging biomarkers in magnetic resonance imaging
AssigneeSiemens Healthcare GmbH
InventorHasan Ertan Cetingul
Life of this patent
Estimating the term…
Abstract
Resolution is enhanced for diffusion MR imaging. The tensors modeling the underlying water diffusion in brain tissues are used to interpolate other diffusion tensors, providing higher resolution diffusion biomarker images. Each diffusion tensor is represented by a pair of elements, the one in an ‘orientation space’ and another in a ‘shape space.’ The tensors are iteratively interpolated by averaging the aforementioned elements in separate mathematical spaces. The weighted average of the shape components of the diffusion tensors is computed in closed form, which decreases the runtime.
Claims13
A method for resolution enhancement for diffusion MR imaging, the method comprising:
- generating first diffusion tensors from the measurements of a diffusion magnetic resonance imaging system, the diffusion tensors being at a scan resolution of the magnetic resonance imaging system;
- interpolating, by a diffusion tensor processor of the magnetic resonance imaging system, second diffusion tensors from the first diffusion tensors, the second diffusion tensors interpolated between the first diffusion tensors, an image of the first and second diffusion tensors having a spatial resolution higher than the scan resolution, the interpolation of the second diffusion tensors from the first diffusion tensors being by Riemannian weighted averaging using a rotation group in three dimensions as an orientation space and a shape space having the first diffusion tensors with a same orientation as elements, wherein the interpolation comprises computing shapes in the shape space in closed form;
- calculating, by the magnetic resonance imaging system, biomarkers of the patient from the image of the first and second diffusion tensors;
- and
- displaying an image of the biomarkers.
Dependencies are inferred from the claim text.