US 10,241,178 B2 · System and method for magnetic resonance fingerprinting at high field strengths

Abstract

A system and method is provided for operating a high-field magnetic resonance (MR) system includes performing a series of data acquisition modules without respiratory gating. Each data acquisition module is formed of a steady-state free precession pulse sequence. Performing the series of data acquisition modules includes varying at least one of an amplitude of an excitation pulse or a repetition time of the steady-state free precession pulse sequence between adjacent data acquisition modules in the series of data acquisition modules to acquire a series of MR data with random or pseudo-random imaging acquisition parameters. The series of MR data is compared to a dictionary of signal evolution profiles to determine a match between the series of MR data with at least one signal evolution profile in the dictionary indicating at least one quantitative parameter in the subject.

Claims20

Dependent claims

A method for operating a high-field magnetic resonance (MR) system to acquire quantitative data from a subject arranged with in the MR system, wherein the method includes steps comprising:

controlling the high-field MR system to perform a preparation module configured to perform one of an inversion pulse or a magnetization preparation;
controlling the high-field MR system to, following the preparation module, perform a series of data acquisition modules without respiratory gating, wherein each data acquisition module is formed of a steady-state free precession pulse sequence and wherein performing the series of data acquisition modules includes varying at least one of an amplitude of an excitation pulse or a repetition time of the steady-state free precession pulse sequence between adjacent data acquisition modules in the series of data acquisition modules to acquire a series of MR data with random or pseudo-random imaging acquisition parameters;
comparing the series of MR data to a dictionary of signal evolution profiles to determine a match between the series of MR data with at least one signal evolution profile in the dictionary;
and
generating a report indicating at least one quantitative parameter in the subject based on the MR data and the match to the at least one signal evolution profile in the dictionary.

2 more elements

A magnetic resonance (MR) system, comprising:

a magnet system configured to generate a static magnetic field of at least 4.7 Tesla about at least a portion of a subject arranged in the MR system;
a gradient system configured to establish at least one magnetic gradient field with respect to the static magnetic field;
a radio frequency (RF) system configured to deliver excitation pulses to the subject and acquire imaging data from the subject;
a computer system programmed to:
control the gradient system and RF system to perform a preparation module including one of an inversion pulse or a magnetization preparation;
control the gradient system and RF system to perform a series of data acquisition modules, wherein each data acquisition module is formed of a steady-state free precession pulse sequence and wherein performing the series of data acquisition modules includes varying at least one of an amplitude of an excitation pulse or a repetition time of the steady-state free precession pulse sequence between adjacent data acquisition modules in the series of data acquisition modules to acquire a series of MR data including respiratory spikes;
and
compare the series of MR data to a dictionary of signal evolution profiles to determine a match between the series of MR data with at least one signal evolution profile in the dictionary;
and
based on the match, determine at least one quantitative parameter of the subject.

7 more elements

Dependencies are inferred from the claim text.

System and method for magnetic resonance fingerprinting at high field strengths

Life of this patent

System and method for magnetic resonance fingerprinting at high field strengths

Life of this patent

Abstract

Claims20