Inline dilution and autocalibration for ICP-MS speciation analysis

A system comprising:

• a first valve, the first valve having a first valve configuration to receive a sample fluid from a sampling device into a holding loop coupled to the first valve;
• a plurality of syringe pumps coupled to the first valve, the plurality of syringe pumps including a carrier syringe pump configured to supply a carrier fluid to the first valve in a second valve configuration, a diluent syringe pump configured to supply a diluent fluid to the first valve in the second valve configuration, and a standard syringe pump configured to supply a standard fluid to the first valve in the second valve configuration, the first valve configured to mix at least two of the diluent fluid, the standard fluid, or the sample fluid to form an inline diluted sample, the first valve configured to deliver the inline diluted sample therefrom;
• and
• a second valve coupled to the first valve, the second valve having a first valve configuration configured to receive the inline diluted sample from the first valve into a sample holding loop coupled to the second valve, the second valve configured to couple to at least one of an eluent source or a carrier fluid source and having a second valve configuration to receive at least one of an eluent fluid from the eluent source or a carrier fluid from the carrier fluid source to transfer the inline diluted sample from the sample holding loop to a speciation column to separate one or more species from the inline diluted sample from respective other species of the inline diluted sample.