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US 10,240,121 B2Granted
Bioreactor system
AssigneeKiyatec Inc.
InventorsMatthew R. Gevaert, David E. Orr, Margaret Rebecca Widener
Life of this patent
Estimating the term…
Abstract
Disclosed herein are bioreactor systems and methods of utilizing said systems.
Claims18
A bioreactor system for 3D passaging of cells comprising;
- at least one cell module defining a first cell culture chamber, an inlet, an outlet, and a port opening, wherein the port opening is on one end of the cell culture chamber;
- and
- a scaffold, located within the at least one cell module, comprising a stacked crosshatch of struts or fibers defining the pores of the scaffold, and a cell anchorage deposited within the pores of the scaffold, wherein cells attach to the cell anchorage.
A method of 3D cell passaging in a bioreactor system, comprising:
- providing a population of cells to be passaged;
- and
- introducing the population of cells into a bioreactor system comprising a scaffold, the scaffold comprising a stacked crosshatch of struts or fibers defining pores in the scaffold, and a cell anchorage deposited within the pores of the scaffold, wherein the cells attach to the cell anchorage.
Dependencies are inferred from the claim text.