Peptide analogs for treating diseases and disorders
AssigneeKeyBioscience AG
InventorsNozer M. Mehta, William Stern, Amy M. Sturmer, Morten Asser Karsdal, Kim Henriksen
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Abstract
Provided herein are methods for the treatment of type I diabetes, Type II diabetes, metabolic syndrome, or obesity, or of appetite suppression, or for mitigating insulin resistance, or for reducing an undesirably high fasting serum glucose level, or for reducing an undesirably high peak serum glucose level, or for reducing an undesirably high peak serum insulin level, or for reducing an undesirably large response to a glucose tolerance test in synergistic combination with metformin. A peptide selected from sequences SEQ ID NO: 12, SEQ ID NO: 15 and SEQ ID NO: 17 are administered.
Claims7
A method for treating osteoporosis, or osteoarthritis in a patient in need of such treatment, comprising administering to the patient an effective amount of a peptide selected from the group consisting of:
- AcCSNLSTCVLGRLSQELHRLQTFPRTDVGA
- SEQ ID NO:
- 12
- NTAcY
- AcCSNLSTCVLGKLSQELHKLQTYPRTDVGA
- SEQ ID NO:
- 15
- NAP-NH2
- SuccCSNLSTCVLGKLSQELHKLQTYPRTDV
- SEQ ID NO:
- 17
- GANAY-NH2.
Dependencies are inferred from the claim text.