Peptides and compositions for treatment of joint damage
AssigneeNovartis AG
InventorsKristen Johnson, Jian Shi
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Abstract
The present invention provides new protease resistant polypeptides, as well as compositions and methods for treating, ameliorating or preventing conditions related to joint damage, including acute joint injury and arthritis.
Claims20
A method of treating or ameliorating arthritis or articular cartilage damage in a subject, the method comprising administering to a joint of the subject a therapeutically effective amount of a polypeptide comprising SEQ ID NO:
- 28.
A method of inducing differentiation of mesenchymal stem cells into chondrocytes, the method comprising contacting mesenchymal stem cells with an effective amount of a polypeptide comprising SEQ ID NO:
- 28.
Dependencies are inferred from the claim text.