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US 10,239,866 B2Granted
Selective methods for the separation of ondansetron and related impurities
AssigneeWaters Technologies Corporation
InventorsPaula Hong, Jennifer Simeone
Life of this patent
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Abstract
The present disclosure generally relates to methods for separating ondansetron and related impurities using CO2-based chromatography.
Claims14
A method of separating ondansetron and at least one related impurity using CO2-based chromatography, comprising
- applying a sample of ondansetron and at least one related impurity to a chromatography column;
- and
- eluting ondansetron and at least one related impurity from the chromatography column using a mobile phase comprising CO2.
Dependencies are inferred from the claim text.