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US 10,239,854 B2Granted
Compounds, compositions and methods for treating or preventing a symptom associated with gout or hyperuricemia
AssigneeArthrosi Therapeutics, Inc.
InventorsShunqi Yan, Li-Tain Yeh, Robert Orr
Life of this patent
Estimating the term…
Abstract
The inventive subject matter provides compounds, compositions and methods for lowering serum acid (sUA) for the treatment of gout, and having reduced liver toxicity, associated with CYP2C9 metabolic pathway.
Claims20
A compound, or a pharmaceutically acceptable salt thereof, of Formula 1:
- wherein:
- X is —OH, —F, or —Cl;
- and
- R1, R2, R3, R4 and R5 are each independently selected from a group consisting of H, deuterium, and F;
- wherein at least one of R1, R2, R3, R4, and R5 is deuterium.
2 more elements
Dependencies are inferred from the claim text.