Back to results
US 10,239,848 B2Granted
Cyclohexenyl compounds, compositions comprising them and uses thereof
AssigneeYissum Research Development Company of the Hebrew University of Jerusalem
InventorsRuth Gallily, Raphael Mechoulam, Aviva Breuer
Life of this patent
Estimating the term…
Abstract
Compositions that include certain phenyl substituted cyclohexenyl compounds are administered to a subject in a method for treating obesity or an associated disease or disorder or in a method of reducing food consumption or body weight.
Claims19
A method for treating obesity or a disease or disorder associated therewith in a subject in need thereof, said method comprising administering to said subject a therapeutically effective amount of a compound of the general formula (I):
- or a salt, enantiomer, diastereomer, or mixture thereof,
- wherein
- R1, R2 and R3 are each independently a (C1-C10)alkyl, (C2-C10)alkenyl or (C2-C10)alkynyl, optionally substituted by at least one substituent each independently selected from the group consisting of hydroxy and halogen;
- R4 is a (C1-C10)alkyl, (C2-C10)alkenyl or (C2-C10)alkynyl, substituted by at least one substituent of general formula (II):
- X is selected from the group consisting of N, N+H, N+(C1-C10 alkyl), O+, S+, P, and P+H;
- and
- R5 and R6 are each independently selected from the group consisting of H, (C1-C10)alkyl, (C2-C10)alkenyl, and (C2-C10)alkynyl, or both R5 and R6 together with X may form a (C3-C8)heterocyclic ring, wherein R5 and R6 each independently is optionally interrupted by at least one group each independently selected from the group consisting of —O—, —NH—, N+(C1-C10 alkyl), and —S—.
4 more elements
Dependencies are inferred from the claim text.