Loading patent…
AssigneeCelgene International II SÀRL
InventorsEsther Martinborough, Marcus F. Boehm, Adam Richard Yeager, Junko Tamiya, Liming Huang, Enugurthi Brahmachary, Manisha Moorjani, Gregg Alan Timony, Jennifer L. Brooks, Robert Peach, Fiona Lorraine Scott, Michael Allen Hanson
Estimating the term…
Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.
A method for treating ulcerative colitis comprising administering an effective amount of a compound having the structure of Formula I-R or I-S or a pharmaceutically acceptable salt thereof to a patient at a frequency and for a duration of time sufficient to provide a beneficial effect to the patient:
A method for treating Crohn's disease comprising administering an effective amount of a compound having the structure of Formula I-R or I-S or a pharmaceutically acceptable salt thereof to a patient at a frequency and for a duration of time sufficient to provide a beneficial effect to the patient:
Dependencies are inferred from the claim text.