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US 10,239,821 B2Granted
Process for the co-production of long chain amino acids and dibasic acids
AssigneeVitaworks IP, LLC
InventorSongzhou Hu
Life of this patent
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Abstract
There is disclosed a process for the co-production of long chain ω-amino acid and long chain dibasic acid, comprising: (1) reacting long chain ketoacid derivative with hydroxylamine or subjecting ketoacid derivative to an ammoximation to yield oxime derivative; (2) subjecting oxime derivative to Beckmann rearrangement to yield a mixture of mixed amide derivatives; (3) hydrolyzing the mixed amide derivatives to produce long chain ω-amino acid and long chain dibasic acid.
Claims10
A process for the co-production of long chain ω-amino acid of formula (V) and long chain dibasic acid of formula (IV), comprising:
- (1) reacting the ketoacid derivative (I) of the formula:
- in a solvent with hydroxylamine or subjecting the ketoacid derivative (I) in a solvent to ammoximation to produce oxime acid derivative (II) of the formula:
- wherein X is OR or NR1R2, wherein OR is C1-C8 monohydric alcohol or polyhydric alcohol, R1 and R2 are each independently hydrogen or C1-C8 alkyl group, m is an integral from 0 to 10, n is an integral from 6 to 20;
- (2) subjecting the oxime derivative (II) in a solvent to Beckmann rearrangement to yield a mixture of amide derivatives (IIIa) and (IIIb)
- and
- (3) hydrolyzing the mixed amide derivatives to long chain ω-amino acid (V) and long chain dibasic acid (IV)
3 more elements
Dependencies are inferred from the claim text.