Self-wetting porous membranes (II)
AssigneePall Corporation
InventorsMarcin Stasiak, Hassan Ait-Haddou
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Abstract
Disclosed is a self-wetting porous membrane comprising an aromatic hydrophobic polymer such as polysulfone and a wetting agent comprising a copolymer of formula A-B or A-B-A, wherein A is a hydrophilic segment comprising a polymerized monomer of the formula (I): CH2═C(R1)(R2), wherein R1 and R2 are as described herein, and B is polyethersulfone, wherein segments B and A are linked through an oxygen atom. Also disclosed is a method of preparing a self-wetting membrane comprising casting a solution containing an aromatic hydrophobic polymer and the wetting agent, followed by subjecting the cast solution to phase inversion. The self-wetting porous membrane finds use in hemodialysis, microfiltration, and ultrafiltration.
Claims17
A self-wetting porous membrane comprising an aromatic hydrophobic polymer and a wetting agent comprising a copolymer of formula A-B or A-B-A,
- wherein A is a hydrophilic segment comprising a polymerized monomer or mixture of monomers, wherein the monomer is of the formula (I):
- CH2═C(R1)(R2) (I),
- wherein R1 is hydrogen or alkyl, and R2 is selected from pyrrolidinonyl, imidazolyl, N-methylimidazolyl, formylamino, formylaminoalkyl, alkylcarbonyloxy, and aminocarbonylalkyl substituted with a zwitterionic group,
- and B is polyethersulfone, wherein segments B and A are linked through an oxygen atom;
- wherein the copolymer has an end group selected from 2-methylpropionitrile, benzoate, laurate, t-butyloxy, and cumyloxy.
A method of preparing a self-wetting porous membrane comprising:
- (i) casting a solution comprising a solvent, an aromatic hydrophobic polymer, and a copolymer of formula A-B or A-B-A, wherein A is a hydrophilic segment comprising a polymerized monomer or mixture of monomers, wherein the monomer is of the formula (I):
- CH2═C(R1)(R2) (I),
- wherein R1 is hydrogen or alkyl, and R2 is selected from pyrrolidinonyl, imidazolyl, N-methylimidazolyl, formylamino, formylaminoalkyl, alkylcarbonyloxy, and aminocarbonylalkyl substituted with a zwitterionic group, and
- wherein the copolymer has an end group selected from 2-methylpropionitrile, benzoate, laurate, t-butyloxy, and cumyloxy,
- and B is polyethersulfone, wherein segments B and A are linked through an oxygen atom, to a desired shape;
- (ii) subjecting the cast solution to phase inversion to form the self-wetting porous membrane;
- and
- (iii) optionally rinsing the self-wetting porous membrane with water.
Dependencies are inferred from the claim text.