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US 10,238,875 B2Granted
Systems and methods for hypertension control
OwnerAdi Mashiachinventor
Life of this patent
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Abstract
Systems and methods for hypertension control via energy delivery to one or more nerves affecting blood pressure are provided. Systems may include implantable devices configured for non-contacting neuromodulation. Implantable devices may be configured for intravascular implantation. Systems may also include external devices configured to communicated with implantable neuromodulation devices, Additional systems may include non-implantable devices for delivering modulation energy and ablation energy to one or more nerves affecting blood pressure.
Claims27
A hypertension therapy device, comprising:
- a carrier configured for deployment in vasculature of a subject;
- an antenna located on the carrier;
- at least one electrode arranged for deployment with the carrier, the at least one electrode being arranged so as to create an electric field when the electrode is energized;
- at least a portion of a circuit arranged for intravascular deployment with the carrier within a blood vessel, the circuit portion being electrically connected to the at least one electrode, the circuit portion further being configured to:
- generate a physiological signal indicating a change in a subject's blood pressure;
- and
- receive a control signal configured to, when the change in the subject's blood pressure exceeds a predetermined threshold, cause an electrical signal providing an initial amount of nerve inhibition to be delivered to the at least one electrode and cause an amplitude and a pulse duration of the electrical signal to be iteratively increased by a predetermined amount at a predetermined rate until a desired amount of nerve inhibition occurs;
- and
- wherein the at least one electrode is configured to emit from within an interior of the blood vessel an electrical field sufficient to modulate signals of at least one nerve located outside of the interior of the blood vessel the vasculature, and
- wherein the at least one electrode includes a plurality of electrode contacts arranged in subsets, the electrode contacts within each subset being electrically connected to each other.
7 more elements
An intravascular device for hypertension therapy, comprising:
- a carrier configured for deployment in a blood vessel via an intravascular deployment mechanism;
- and
- a plurality of electrode contacts arranged circumferentially about the carrier;
- wherein the electrode contacts are configured to receive energy from a source and to radiate energy via the plurality of electrical contacts to a plurality of locations on a wall of the blood vessel,
- wherein the electrode contacts are arranged in subsets, the electrode contacts within each subset being electrically connected to each other, and
- a circuit electrically connected to the electrode contacts and configured to:
- generate a physiological signal indicating a change in a subject's blood pressure;
- and
- receive a control signal configured to, when the change in the subject's blood pressure exceeds a predetermined threshold, cause an electrical signal providing an initial amount of nerve inhibition to be delivered to the electrode contacts and cause an amplitude and a pulse duration of the electrical signal to be iteratively increased by a predetermined amount at a predetermined rate until a desired amount of nerve inhibition occurs.
6 more elements
Dependencies are inferred from the claim text.