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US 10,238,775 B2Granted
Bone repair material
AssigneeStraumann Holding AG
InventorsCorinna Mauth, Aaldert-Rens Molenberg
Life of this patent
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Abstract
Sliceable bone repair material is a porous block-shaped scaffold containing a hydrogel, wherein the hydrogel is formed by Michael type addition of at least two precursor molecules. Said scaffold is made of a synthetic ceramic material and has interconnected macropores having a diameter above 100 μm. In addition said scaffold has a total porosity of 60 to 80%. The total volume of the hydrogel is smaller than the total volume of the interconnected macropores.
Claims16
A method for preparing a bone repair material, the method comprising:
- a. mixing an aqueous solution comprising a first precursor with an aqueous solution comprising a second precursor to form a mixture, a total concentration of the first precursor and the second precursor in the mixture being less than an equilibrium concentration of a hydrogel;
- b. adding the mixture to a porous block-shaped scaffold, the scaffold being made of a synthetic ceramic material and comprising interconnected macropores having a diameter of at least 100 μm, the scaffold having a total porosity in a range of from 60 to less than 80%;
- and
- c. removing water from the porous block-shaped scaffold containing the mixture to allow a Michael type addition reaction between the first precursor and the second precursor to produce a crosslinked polyethylene glycol hydrogel within the porous block-shaped scaffold.
1 more element
Dependencies are inferred from the claim text.