Methods of modulating immune system responses
AssigneeThe Governing Council of the University of Toronto
InventorsScott Gray-Owen, Ryan Gaudet, Rebecca Malott
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Abstract
Novel methods and uses for modulating immune responses are provided. The methods and uses involve the use of a TIFA activator such heptose-1,7-5 bisphosphate or an analog or derivative thereof. The methods may be used to activate, inhibit or otherwise modify an immune response so as to either prevent or treat infectious or inflammatory diseases or cancer. Also provided are methods to identify compounds capable of modulating immune responses.
Claims10
A method of enhancing the immune responsiveness in a subject comprising administering an effective amount of a TIFA activator to a subject in need thereof.
A pharmaceutical composition for enhancing an immune response comprising an effective amount of a heptose-1,7-bisphosphate and a carrier.
Dependencies are inferred from the claim text.