US 10,238,702 B2 · Pharmaceutical composition, preparation method therefor and use thereof

Abstract

The pharmaceutical composition is a formulation prepared by the raw materials in parts by weight: 1-300 parts of chlorogenic acid and 1-50 parts of Ganoderma lucidum spore oil, and the preparative process for said pharmaceutical composition was provided. Chlorogenic acid can be used compatibly with Ganoderma lucidum spore oil, with a synergistic effect. Inclusion technique is applied in product development to improve stability of oily liquid material Ganoderma lucidum spore oil and solid material chlorogenic acid obtained from the extract of Eucommia leaves. After inclusion by the inclusion technology, the liquid drugs become powder, and thus easily oxidized natural products could be protected. Moreover, the damage for active ingredients caused by air can be prevented, and the stability and the taste may get improved.

Claims5

Dependent claims

A pharmaceutical composition, comprising:

active ingredients and a pharmaceutically acceptable excipient or an auxiliary constituent, wherein:
the active ingredients consist of chlorogenic acid and Ganoderma lucidum spores oil, the chlorogenic acid and Ganoderma lucidum spores oil having a weight ratio of 10:1 to 6:1;
the pharmaceutically acceptable excipient comprises a filling agent and a diluent agent;
the filling agent is selected from the group consisting of lactose, glucose, sorbitol, mannitol, maltitol, xylitol, and a mixture thereof;
the diluent agent is selected from the group consisting of starch, microcrystalline cellulose, mannitol, and a mixture thereof, and
wherein said composition is a buccal preparation or an oral preparation.

3 more elements

Dependencies are inferred from the claim text.

Pharmaceutical composition, preparation method therefor and use thereof

Life of this patent

Pharmaceutical composition, preparation method therefor and use thereof

Life of this patent

Abstract

Claims5