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US 10,238,659 B2Granted
Fatty liver disease treatment using glucocorticoid and mineralocorticoid receptor antagonists
AssigneeCorcept Therapeutics, Inc.
InventorsJoseph K. Belanoff, Hazel Hunt, Onno C. Meijer, José van den Heuvel
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Abstract
The present invention provides treatment of fatty liver disease using a class of pyrimidinedione cyclohexyl compounds.
Claims14
A method of treating fatty liver disease, comprising administering to a subject in need thereof, a therapeutically effective amount of a compound of Formula Id, thereby treating the fatty liver disease, wherein the compound of Formula Id has the structure:
- wherein
- each R1a is independently H, C1-6 alkyl, halogen, or C1-6 haloalkyl;
- R2 is H, or C1-6 alkyl;
- and
- each R4 is H, C1-6 alkyl, halogen, or C1-6 haloalkyl;
- or salts or isomers thereof.
3 more elements
Dependencies are inferred from the claim text.