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US 10,238,624 B2Granted
Composition for activating longevity genes, containing kojic acid derivative as active ingredient
AssigneeAmorepacific Corporation
InventorsHyun Jung Kim, Ji Hyun Kim, Jue Won Kim, Ho Sik Rho, Hyun Seo Kang
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Abstract
Disclosed is a composition for activating longevity genes, particularly, a Sirt-1, Klotho, XPD, ERCC8 or FoxO3a gene, containing a kojic acid derivative as an active ingredient. The composition activates longevity genes, thereby having anticancer, lifetime extension, skin moisturization or skin barrier strengthening effects.
Claims6
A method for activating one or more genes selected from a group consisting of Sirt-1, Klotho, XPD, ERCC8, and FoxO3a, comprising administering an effective amount of koiyl methylenedioxycinnamate represented by Chemical Formula 2
- a salt thereof, a hydrate thereof, or a solvate thereof to a subject in need thereof,
- Wherein the method is for extending the lifespan of skin cells, or for inhibiting a skin cancer.
Dependencies are inferred from the claim text.