Compositions and methods for diagnosis and treatment of anemia
AssigneeThe United States of America as represented by the Secretary of the Navy
InventorsStephanie Kay Venn-Watson, Mark Baird
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Abstract
Compositions including a fatty acid, such as an odd chain fatty acid or a very long even chain fatty acid, and salts and derivatives thereof, and methods for treatment and prophylaxis of conditions related to anemic conditions, are provided, including compositions and methods for treating anemic conditions such as hemolytic anemia and anemia of chronic disease, and other related conditions.
Claims13
A method of treatment of an anemic condition, wherein the anemic condition is selected from the group consisting of hemolytic anemia, thalassemia, hereditary spherocytosis, hereditary elliptocytosis, glucose-6-phosphate dehydrogenase deficiency, pyruvate kinase deficiency, immune hemolytic anemia, alloimmune hemolytic anemia, drug-induced hemolytic anemia, mechanical hemolytic anemia, paroxysmal nocturnal hemoglobinuria, anemia of chronic disease, anemia, aplastic anemia, congenital hypoplastic anemia, Diamond-Blackfan anemia, Fanconi anemia, iron deficiency anemia, anemia of abnormal RBC size, megaloblastic anemia, microcytic anemia, vitamin deficiency anemia, pernicious anemia, anemia of RBC mutation, sideroblastic anemia, and sickle cell anemia, comprising:
- administering to a patient in need thereof, a composition comprising at least ten percent of one or more odd-chain saturated fatty acids, or pharmaceutically acceptable salts thereof, wherein the one or more odd-chain saturated fatty acids are selected from the group consisting of C15:0, C17:0, and combinations thereof.
Dependencies are inferred from the claim text.