US 10,238,611 B2 · Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid

Abstract

The invention relates to methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid (3APS) in a subject, preferably a human subject. The invention encompasses compound that will yield or generate 3APS, either in vitro or in vivo. Preferred compounds include amino acid prodrugs of 3APS for use, including but not limited to the prevention and treatment of Alzheimer's disease.

Claims9

Dependent claims

A compound of Formula VIII:

wherein said compound is selected from the group consisting of:
or a pharmaceutically acceptable salt of any of the foregoing.

Dependencies are inferred from the claim text.

Facts

Application

15/293,965Filed 14 Oct 2016 · continuation

Priority

12 Oct 2006

Published

US 2017/0095430 A16 Apr 2017

Granted

26 Mar 2019

Term ends

Not estimatedThe source records don’t support an estimate.

Classification42 codes

A61K 31/145
Amines: having sulfur, e.g. thiurams , Sulfinylamines , Sulfonylamines
A61K 47/54
The non-active ingredient being a modifying agent: the modifying agent being an organic compound
A61K 47/542
The modifying agent being an organic compound: carboxylic acids, e.g. a fatty acid or an amino acid
A61K 47/545
The modifying agent being an organic compound: heterocyclic compounds

Family

Application60/851,039Us provisional application · filed 12 Oct 2006

Application60/911,459Us provisional application · filed 12 Apr 2007

Application11/871,639Parent of this continuation · filed 12 Oct 2007

Application14/246,894Parent of this continuation · filed 7 Apr 2014

US 8,748,656 B2Parent of this continuation · filed 10 Jun 2014

US 2017/0095430 A1Pre-grant publication · published 6 Apr 2017

US 9,499,480 B2Parent of this continuation

US 2008/0146642 A1Published application

US 2014/0220122 A1Published application

US 10,238,611 B2This patent

From the US filing history. Foreign family members aren’t listed.

Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid

Life of this patent

Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid

Life of this patent

Abstract

Claims9