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US 10,238,609 B2Granted
Cyanide antidote compositions and methods of use
AssigneeSam Houston State University
InventorsIlona Petrikovics, Csaba Jaszberenyi
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Abstract
Cyanide antidote compositions and methods of use are described herein. A cyanide antidote composition may include a sulfur analog, sulfur analog derivative, or a pharmaceutically acceptable derivative of a sulfur analog.
Claims11
A method of treating cyanide intoxication in a subject, comprising:
- administrating to a subject who would benefit from such treatment a therapeutically effective amount of a sulfur analog, or pharmaceutically acceptable derivative of a sulfur analog in an amount sufficient to convert at least some cyanide to thiocyanate to detoxify the subject, wherein the sulfur analog has the structure
- R1—Sn—R2 (I)
- where R1 is R3—SO2—;
- R2 is R4—SO2— or R5;
- and n is 1 to 8;
- where R3 is an alkyl moiety or an aryl moiety;
- where R4 is an alkyl moiety or an aryl moiety;
- and
- R5 is an alkyl moiety or an aryl moiety.
6 more elements
Dependencies are inferred from the claim text.