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US 10,238,606 B2Granted
Pharmaceutical compositions for the treatment of Helicobacter pylori
AssigneeRedHill Biopharma Ltd.
InventorsReza Fathi, Gilead Raday, Guy Goldberg, Patrick Gosselin
Life of this patent
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Abstract
Single oral solid dosage form comprising an immediate release first dosage composition having at least two antibiotic agents and a delayed release second dosage composition having a proton pump inhibitor are provided herein. The single oral solid dosage form according to some aspects of the invention can be used for the treatment of disorders associated with infection by H. pylori or the prevention of recurrence of disorders associated with infection by H. pylori.
Claims6
A kit comprising:
- a 14 day supply of capsules for eradicating H. pylori infection with an effectiveness greater than 80%, the 14 day supply including 168 all-in-one capsules filled with minitablets, wherein each capsule comprises 12.5 mg rifabutin/250 mg amoxicillin mixed minitablets and 10 mg omeprazole minitablets;
- and
- instructions to administer orally 4 capsules from the 14 day supply three times daily for a total daily oral dose of 150 mg rifabutin, 3000 mg amoxicillin, and 120 mg omeprazole for 14 days.
Dependencies are inferred from the claim text.