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US 10,238,601 B2Granted
Particles for use in a pharmaceutical composition
AssigneeVectura Limited
InventorsJohn Nicholas Staniforth, David Alexander Vodden Morton
Life of this patent
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Abstract
The invention provides a method of making a composition for inhalation which includes the step of mixing particles of additive material having a diameter of not more than 2 μm with active particles, wherein the additive material is suitable for promoting the dispersal of active particles upon aerolisation of a dry powder in a dry powder inhaler.
Claims16
A method of making a composition for inhalation comprising:
- mixing particles of additive material having a diameter of more than 2 μm with active particles, wherein the additive material comprises magnesium stearate;
- and
- pressing the particles of additive material to the surfaces of the active particles by a high shear process, wherein the high shear process comprises compressing the mixture of active particles and particles of additive material in a gap of fixed predetermined width.
Dependencies are inferred from the claim text.