Acquisition and analysis techniques for improved outcomes in optical coherence tomography angiography

A method for acquiring wide-field optical coherence tomography (OCT) angiography image data of an eye using an OCT system having an adjustable refractive correction, comprising:

• acquiring a first OCT angiography volume dataset with the OCT system at a first refractive correction over a first region of the eye, said OCT system including a light source generating a light beam that is divided into sample and reference paths, said OCT system including a detector for monitoring light received from the sample and reference paths, said detector generating output signals in response to the monitored light, said OCT system further including a processor for analyzing the output signals;
• in said processor, determining a curvature of the eye from the first volume dataset near an edge of the first region;
• in said processor, determining a second refractive correction based on the determined curvature;
• acquiring a second OCT angiographic volume dataset with the OCT system at the second refractive correction over a second region of the eye different from the first region, said second region at least partially overlapping the edge of the first region;
• generating a single image of the eye from the first and second datasets;
• and
• storing in the processor the generated image or a further analysis thereof or displaying on a display the generated image or a further analysis thereof.